17281-92-4Relevant articles and documents
Identification of the products of reaction between pyridoxal phosphate and amiclenomycin and other related 1-amino-cyclohexa-2,5-dienes
Mann, Stéphane,Lesage, Denis,Tabet, Jean-Claude,Marquet, Andrée
, p. 5209 - 5214 (2003)
Amiclenomycin, a natural product containing the 1-amino cyclohexa-2,5-diene moiety is an inhibitor of 7;8-diaminopelargonic acid aminotransferase, a pyridoxal phosphate (PLP) dependent enzyme involved in biotin biosynthesis. The postulated mechanism implies the aromatisation of the Schiff base formed between PLP and amiclenomycin. Aromatic adducts have been obtained by heating PLP with amiclenomycin and other related 1-amino cyclohexa-2,5-dienes. They were fully characterized by UV-visible and ESI mass spectrometry and provide standards for identification of the enzyme-derived products.
Thermodynamic Equilibrium Constants for Pyridoxal and Pyridoxal 5'-Phosphate in Dioxane-Water Mixtures
Llor, Juan,Sanchez-Ruiz, Jose M.,Cortijo, Manuel
, p. 951 - 956 (2007/10/02)
The electronic absorption spectra of pyridoxal and pyridoxal 5'-phosphate have been obtained in water-dioxane mixtures (0-70percent v/v) at 25 deg C, and resolved using log-normal curves.The thermodynamic values of the hydration, hemiacetal, and tautomeric equilibrium constants together with the microscopic pK values for these compounds in all the mixtures studied could then be obtained.The variation of these pK values according to solvent polarity fits Marshall's model satisfactorily.
Coordination Modes of Histidine. 2. Stereochemistry of the Reaction between Histidine Derivatives and Pyridoxal Analogues. Conformational Properties of Zinc(II) Complexes of Histidine Schiff Bases
Casella, Luigi,Gullotti, Michele
, p. 6338 - 6347 (2007/10/02)
Pyridoxal reacts with L-histidine, L-histidine methyl ester, histamine and Nτ-methylhistamine to form 4,5,6,7-tetrahydropyridoimidazole compounds through the formation of Schiff base intermediates.The 4,6-trans isomers of the products ar