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17297-82-4

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  • 1-Piperazineethanol,4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-, hydrochloride (1:2)

    Cas No: 17297-82-4

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17297-82-4 Usage

Originator

Pervetral, Homburg , W. Germany ,1962

Manufacturing Process

32 parts of 10-(γ-N-piperazinopropyl)-4-azaphenthiazine in 200 cc of butanol with 9 parts of ethylene chlorohydrin and 14 parts of finely powdered potash are heated for 4 hours under reflux while stirring vigorously. After cooling, extraction is carried out with dilute hydrochloric acid, the substance is finally washed with water and the combined hydrochloric acid aqueous phase is washed twice with ether. The base is then liberated with concentrated sodium hydroxide solution and taken up in chloroform. The chloroform solution is dried with potash and concentrated by evaporation. 26.4 parts of (10-γ-N-Bhydroxyethylpiperazino-N1-propyl)-4-azaphenthiazine are distilled over at 280°C to 300°C/6 mm. The dihydrochloride is obtained in isopropanol with isopropanolic hydrochloric acid. The product melts at 218°C to 220°C.

Therapeutic Function

Antiemetic

Safety Profile

A poison by intravenous, intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx, SOx, and Cl-.

Check Digit Verification of cas no

The CAS Registry Mumber 17297-82-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,2,9 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17297-82:
(7*1)+(6*7)+(5*2)+(4*9)+(3*7)+(2*8)+(1*2)=134
134 % 10 = 4
So 17297-82-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H26N4OS.2ClH/c25-16-15-23-13-11-22(12-14-23)9-4-10-24-17-5-1-2-6-18(17)26-19-7-3-8-21-20(19)24;;/h1-3,5-8,25H,4,9-16H2;2*1H

17297-82-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Oxypendyl dihydrochloride

1.2 Other means of identification

Product number -
Other names perthipendyl,dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17297-82-4 SDS

17297-82-4Upstream product

17297-82-4Downstream Products

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