173485-12-6 Usage
Description
IANBD AMIDE, also known as 4-((Iodoacetyl)amino)butanoic acid, is a versatile chemical compound that belongs to the family of amides. It is widely used in biochemistry and molecular biology research for its unique properties as a fluorescent dye and a thiol-reactive reagent. With a strong emission at around 530 nm, IANBD AMIDE is an invaluable tool for fluorescence resonance energy transfer (FRET) studies, enabling the investigation of protein conformational changes and measuring distances between molecules. Its ability to label and study the behavior of cysteine residues within biomolecules further expands its utility in various applications, such as the study of protein-protein interactions, protein folding, and membrane dynamics.
Uses
Used in Biochemistry and Molecular Biology Research:
IANBD AMIDE is used as a fluorescent probe for studying protein conformational changes and measuring distances between molecules. Its strong emission at 530 nm makes it a valuable tool for fluorescence resonance energy transfer (FRET) studies, allowing researchers to gain insights into the structural dynamics of proteins and their interactions with other biomolecules.
Used in Protein-Protein Interaction Studies:
IANBD AMIDE is used as a labeling agent for cysteine residues within biomolecules, enabling the investigation of protein-protein interactions. Its thiol-reactive nature allows for the specific labeling of cysteine residues, providing a means to track and analyze the behavior of proteins in various biological processes.
Used in Protein Folding Studies:
IANBD AMIDE is used as a probe to study protein folding, as its fluorescent properties allow for the monitoring of conformational changes during the folding process. This helps researchers understand the mechanisms underlying protein folding and the factors that influence it.
Used in Membrane Dynamics Research:
IANBD AMIDE is used as a tool to investigate membrane dynamics, particularly the behavior of proteins and other biomolecules within the lipid bilayer. Its ability to label and study the behavior of cysteine residues in membrane proteins provides insights into the structural and functional aspects of membrane-associated processes.
Check Digit Verification of cas no
The CAS Registry Mumber 173485-12-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,4,8 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 173485-12:
(8*1)+(7*7)+(6*3)+(5*4)+(4*8)+(3*5)+(2*1)+(1*2)=146
146 % 10 = 6
So 173485-12-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H14IN5O4/c1-16(5-6-17(2)10(19)7-13)8-3-4-9(18(20)21)12-11(8)14-22-15-12/h3-4H,5-7H2,1-2H3
