1767-46-0Relevant articles and documents
L-(-)-menthol in the synthesis of key synthons for optically active methyl-branched insect pheromones
Ishmuratov,Yakovleva,Ganieva,Amirkhanov,Tolstikov
, p. 719 - 721 (2005)
A synthesis of optically active 4S-methylhexanal, 1-bromo-3S-methylheptane, and 1-bromo-3S-methylundecane, which are key synthons for several methyl-branched insect pheromones, that is based on chemically selective transformations of 6-tosyloxy- and 6-iodoisopropyl-4R-methylhexanoates that are available from L-(-)-menthol was proposed. 2005 Springer Science+Business Media, Inc.
Novel Caprolactones from a Marine Streptomycete
Stritzke, Katja,Schulz, Stefan,Laatsch, Hartmut,Helmke, Elisabeth,Beil, Winfried
, p. 395 - 401 (2007/10/03)
Two new caprolactones, (R)-10-methyl-6-undecanolide (1) and (6R,10S)-10-methyl-6-dodecanolide (2), were identified in the lipid extract of a marine streptomycete (isolate B6007). Their structures were proposed on the basis of GC-MS experiments and proved by synthesis. The absolute configuration of the compounds was established by comparison of the natural and synthetic stereoisomers using chiral gas chromatography. These caprolactones show a moderate phytotoxicity and a promising activity against cancer cells with concomitant low general cytotoxicity.
Highly regio-, (E)-stereo-, and diastereoselective SN2′ addition of organocuprates to chiral allylic cyclic carbonates
Kang, Suk-Ku,Lee, Dong-Ha,Sim, Hyeong-Su,Lim, Jong-Suk
, p. 91 - 94 (2007/10/02)
Reaction of the cyclic carbonates of acyclic vinyl diols with RCu(CN)Li· BF3, RCu(CN)MgBr·BF3, or RMgBr·CuI (cat) in THF at -78°C proceeded in SN2′ fashion and resulted in the formation of alkylated (E)-allylic alcohols wi