17852-28-7 Usage
Description
2-amino-5-methylbenzophenone is an aromatic ketone belonging to the class of organic compounds. It is characterized by the molecular formula C14H13NO and a molecular weight of 211.26 g/mol. 2-amino-5-methylbenzophenone is known for its role as an intermediate in the synthesis of various products, including pharmaceuticals, dyes, and other organic compounds.
Uses
Used in Pharmaceutical Industry:
2-amino-5-methylbenzophenone is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs and medicinal compounds.
Used in Dye Industry:
In the dye industry, 2-amino-5-methylbenzophenone is utilized as an intermediate in the production of dyes, where its chemical properties are essential for creating colorants with specific characteristics.
Used in Cosmetic Industry:
2-amino-5-methylbenzophenone is used as a UV filter in sunscreen formulations to protect the skin from harmful UV radiation. It effectively absorbs UVB and short UVA rays, making it a valuable ingredient in sunscreen products. However, its use in cosmetic products is strictly regulated due to potential toxicity and environmental concerns.
Safety and Handling:
It is crucial to handle 2-amino-5-methylbenzophenone with care and adhere to safety guidelines when working with this compound to mitigate any risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 17852-28-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,8,5 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17852-28:
(7*1)+(6*7)+(5*8)+(4*5)+(3*2)+(2*2)+(1*8)=127
127 % 10 = 7
So 17852-28-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H13NO/c1-10-7-8-13(15)12(9-10)14(16)11-5-3-2-4-6-11/h2-9H,15H2,1H3
17852-28-7Relevant articles and documents
One-Pot Synthesis of 2-Aminobenzophenones from 2-Alkynyl Arylazides Catalyzed by Pd and Cu Precursors
Fan, Hui,Xu, Shijie,Yang, Fan,Zhang, Xiaoxiang,Zhao, Xuechun
supporting information, p. 4555 - 4558 (2021/08/30)
We describe a novel one-pot three-step reaction of 2-alkynyl arylazides through palladium-catalyzed formation of 3-hydroxy-3-phenylindolin-2-ones followed by hydrolysis of amide bonds and copper-catalyzed decarboxylation to give 2-aminobenzophenones. This synthetic method works well with various 2-alkynyl arylazides and affords the products in moderate to good yields under mild reaction conditions.
Visible Light Induced Cyclization to Spirobi[indene] Skeletons from Functionalized Alkylidienecyclopropanes
Li, Quanzhe,Liu, Jiaxin,Shi, Min,Wei, Yin
, (2020/03/26)
In this paper, we revealed a metal-free and visible light photoinduced method for the rapid construction of spirobi[indene] skeletons, providing a simple and efficient way for easy access to spirobi[indene] scaffolds under mild conditions along with a broad substrate scope and good functional group tolerance.
Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-spirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution
Li, Quanzhe,Yu, Liuzhu,Wei, Yin,Shi, Min
, p. 9282 - 9296 (2019/08/12)
A synthetic method for the construction of diiodinated all-carbon spirobiindene derivatives has been developed from the reaction of propargyl alcohol-tethered alkylidenecyclopropanes with iodine. The reaction proceeded through an iodination-initiated cascade intramolecular enyne cyclization and electrophilic aromatic substitution reaction process in 1,2-dichloroethane upon heating, giving desired spirocyclic products in moderate to excellent yields. Further transformation of the obtained products has also been presented.
