179055-95-9 Usage
Description
3-(1-methyl-1h-pyrazol-5-yl)benzonitrile, a chemical compound with the formula C12H10N4, is known for its unique molecular structure and functional groups. It is a versatile building block in organic synthesis and pharmaceutical research, with potential applications in the development of new drugs and materials. Its distinctive properties and reactivity also make it a candidate for use in organic electronics and materials science, where further research and testing are required to explore its full potential.
Uses
Used in Pharmaceutical Research:
3-(1-methyl-1h-pyrazol-5-yl)benzonitrile is used as a key intermediate in the synthesis of various pharmaceutical compounds for its unique molecular structure and functional groups, contributing to the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 3-(1-methyl-1h-pyrazol-5-yl)benzonitrile serves as a valuable precursor for the creation of complex organic molecules, leveraging its reactivity and structural features to form a wide range of chemical products.
Used in Organic Electronics:
3-(1-methyl-1h-pyrazol-5-yl)benzonitrile is used as a component in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and organic solar cells, due to its electronic properties and potential for molecular engineering.
Used in Materials Science:
In materials science, 3-(1-methyl-1h-pyrazol-5-yl)benzonitrile is utilized for the design and synthesis of novel materials with specific properties, such as high thermal stability or unique optical characteristics, by taking advantage of its chemical reactivity and structural attributes.
Further research and testing are essential to fully understand the potential uses and properties of 3-(1-methyl-1h-pyrazol-5-yl)benzonitrile, ensuring its safe and effective application across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 179055-95-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,0,5 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 179055-95:
(8*1)+(7*7)+(6*9)+(5*0)+(4*5)+(3*5)+(2*9)+(1*5)=169
169 % 10 = 9
So 179055-95-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H9N3/c1-14-11(5-6-13-14)10-4-2-3-9(7-10)8-12/h2-7H,1H3
179055-95-9Relevant articles and documents
Palladium-catalysed direct diarylations of pyrazoles with aryl bromides: A one step access to 4,5-diarylpyrazoles
Takfaoui, Abdelilah,Zhao, Liqin,Touzani, Rachid,Dixneuf, Pierre H.,Doucet, Henri
, p. 1697 - 1701 (2014/03/21)
The palladium-catalysed direct arylation of pyrazoles with aryl halides, using PdCl(C3H5)(dppb)/KOAc catalyst, reveals a similar reactivity of C4 and C5 CH bonds of pyrazoles, whereas the C3 CH bond is almost unreactive, and gives ac
Inhibitors of acyl-coA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N- (heteroaryl-substituted benzyl)-N'-arylureas
Tanaka, Akira,Terasawa, Takeshi,Hagihara, Hiroyuki,Sakuma, Yuri,Ishibe, Noriko,Sawada, Masae,Takasugi, Hisashi,Tanaka, Hirokazu
, p. 2390 - 2410 (2007/10/03)
A series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylurea and related derivatives represented by 2 and 3 have been prepared and evaluated for their ability to inhibit acyl-CoA:cholesterol O-acyltransferase in vitro and to lower plasma cholesterol levels in cholesterol-fed rats in vivo. Among these novel compounds, the type 3 series was superior. A pyrazol-3-yl group on the N-benzyl group of this trisubstituted urea (i.e. 3, Ar1 = pyrazol-3- yl) was identified as a heteroaromatic ring providing a good profile of biological activity. As a result of optimization of the combination with the N-alkyl group (R) and N-aryl group (At3), compound 3aq (FR186054) was identified as a new, orally efficacious ACAT inhibitor, which exhibited potent in vitro ACAT inhibitory activity (rabbit intestinal microsomes IC50 = 99 nM) and excellent hypocholesterolemic effects in cholesterol-fed rats, irrespective of administration mode (ED50 = 0.046 mg/kg dosed via the diet, ED50 = 0.44 mg/kg administered by gavage in PEG400 vehicle). Moreover, a toxicological study revealed compound 3aq to be nontoxic to the adrenal glands of dogs when tested at a single dose of 10 mg/kg po.