18071-35-7 Usage
General Description
DI-N-PROPYLAMINOACETONITRILE is a chemical compound with the formula C8H16N2, commonly used as a reagent in organic synthesis and pharmaceutical research. It is a clear, colorless liquid with a faint, amine-like odor, and is typically stored and handled under strict safety precautions due to its toxic and potentially hazardous nature. DI-N-PROPYLAMINOACETONITRILE is commonly used in the production of various pharmaceuticals and agrochemicals as an intermediate and as a building block for the creation of complex organic molecules. It is also utilized as a precursor in the synthesis of other important chemicals, and its versatility and relatively straightforward synthesis make it a valuable and widely used reagent in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 18071-35-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,7 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18071-35:
(7*1)+(6*8)+(5*0)+(4*7)+(3*1)+(2*3)+(1*5)=97
97 % 10 = 7
So 18071-35-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H16N2/c1-3-6-10(7-4-2)8-5-9/h3-4,6-8H2,1-2H3
18071-35-7Relevant articles and documents
Asada,H. et al.
, p. 1545 - 1546 (1979)
Syntheses of R and S isomers of AF-DX 384, a selective antagonist of muscarinic M2 receptors
Martin, Juliette,Deagostino, Annamaria,Perrio, Cecile,Dauphin, Francois,Ducandas, Christophe,Morin, Christophe,Desbene, Paul-Louis,Lasne, Marie Claire
, p. 591 - 600 (2007/10/03)
Enantiomers of 5,11-dihydro-11-[2-[2-[(N,N-dipropylaminomethyl)piperidin-1-yl]ethylamino]-carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one (AF-DX 384) 1, have been synthesized from (S)-(+) and (R)-(-)-2-[N,N-dipropylaminomethyl]piperidine 4. The enantiomeric excess of 1 has been determined by capillary electrophoresis by using the α-highly sulphated cyclodextrin (α-HSCD) as chiral selector within the running electrolyte. (S)-(+)-(4) was prepared from (S)-(-)-pipecolic acid in a 4-step procedure (overall yield: 30%, ee: 99%) and (R)-(-)-AF-DX 384 from (R)-(+)-pipecolic acid. The (R)-(-) isomer exhibited in vitro a 23-fold higher affinity than its enantiomer (S)-(+) towards muscarinic receptors of subtype 2. Copyright (C) 2000.
