18300-68-0 Usage
General Description
1-(4-Aminophenyl)ethanone semicarbazone is a chemical compound consisting of a semicarbazone group attached to a 1-(4-aminophenyl)ethanone molecule. It is commonly used in pharmaceutical research as it exhibits potential anti-cancer properties. Furthermore, studies have shown that it has significant inhibitory effects on colon cancer cell growth. Additionally, it has been investigated for its potential use in treating other types of cancer, such as breast cancer and leukemia. The compound's chemical structure and properties make it a promising candidate for further exploration in the development of anti-cancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 18300-68-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,3,0 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 18300-68:
(7*1)+(6*8)+(5*3)+(4*0)+(3*0)+(2*6)+(1*8)=90
90 % 10 = 0
So 18300-68-0 is a valid CAS Registry Number.
18300-68-0Relevant articles and documents
Evaluation of semicarbazones for anticonvulsant and sedative-hypnotic properties
Pandeya,Aggarwal,Jain
, p. 300 - 302 (2007/10/03)
A series of semicarbazones and thiosemicarbazones were synthesized and evaluated for anti-convulsant activity. Some compounds provided significant protection against Maximal Electroshock (MES) and subcutaneous strychnine induced seizures. Compound 1 was the most active in the series with activity in a dose of 30 mg/kg in the strychnine seizure pattern test and an ED50 of 10 mg/kg in the MES test. Hence it could serve as a prototype molecule for future development. Also compounds with a p-nitrophenyl substitution in place of the amino hydrogen of semicarbazone moiety showed activity in a dose of 30 mg/kg and an ED50 of 83 mg/kg in the MES test.
