183606-89-5Relevant articles and documents
Amino acid derived thiane oxide and dioxide systems as disposable templates: Synthesis of α-amino ketones, anti-amino alcohols and an amino cyclopentenone
Gamble, Mark P.,Giblin, Gerard M. P.,Montana, John G.,O'Brien, Peter,Ockendon, Timothy P.,Taylor, Richard J. K.
, p. 7457 - 7460 (2007/10/03)
Sulfones and sulfoxides synthesised from methionine and homocysteine thiolactone have been cyclised to amino ketones using potassium bis(trimethylsilyl)amide. Ramberg-Backlund chemistry on one of the sulfones gave an amino cyclopentenone whereas acyclic α-amino ketones and anti-amino alcohols were obtained by Raney nickel desulfurisation of the sulfoxides.