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184951-90-4

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  • 1H-Benzotriazole-1-butanoicacid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-6-nitro-g-thioxo-, 1,1-dimethylethylester, (bS)-

    Cas No: 184951-90-4

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  • 1H-Benzotriazole-1-butanoicacid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-6-nitro-g-thioxo-, 1,1-dimethylethylester, (bS)-

    Cas No: 184951-90-4

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184951-90-4 Usage

General Description

Boc-ThionoGlu(OtBu)-1-(6-nitro)benzotriazolide is a compound used in peptide synthesis as a coupling reagent. It is a derivative of Boc-protected thionoglutamic acid that is activated by 1-(6-nitro)benzotriazolide. This reagent facilitates the formation of peptide bonds between amino acids, allowing for the efficient and selective synthesis of peptides. Boc-ThionoGlu(OtBu)-1-(6-nitro)benzotriazolide is commonly used in solid-phase peptide synthesis and is known for its high coupling efficiency and low racemization rates. It has been widely utilized in the pharmaceutical industry and academic research for the production of biologically active peptides and peptide-based drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 184951-90-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,9,5 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 184951-90:
(8*1)+(7*8)+(6*4)+(5*9)+(4*5)+(3*1)+(2*9)+(1*0)=174
174 % 10 = 4
So 184951-90-4 is a valid CAS Registry Number.

184951-90-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl (4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-(6-nitrobenzotriazol-1-yl)-5-sulfanylidenepentanoate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:184951-90-4 SDS

184951-90-4Downstream Products

184951-90-4Relevant articles and documents

Thiopeptide synthesis. α-Amino thionoacid derivatives of nitrobenzotriazole as thioacylating agents

Ashraf Shalaby,Grote, Christopher W.,Rapoport, Henry

, p. 9045 - 9048 (2007/10/03)

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