1850-57-3 Usage
Chemical structure
A complex structure containing four methoxy groups and derived from benzo[a]heptalene, a polycyclic aromatic hydrocarbon.
Classification
An organic molecule.
Biological activities
Known for its potential antioxidant, anti-inflammatory, and anticancer properties.
Research interest
The compound's unique structure and potential biological activities make it a subject of interest for further research in the fields of medicinal chemistry and drug development.
Functional groups
Contains four methoxy groups (-OCH3) attached to the aromatic ring.
Aromaticity
Part of the polycyclic aromatic hydrocarbon family, which is known for its aromatic character.
Hydrogenation
The presence of a dihydro (partially hydrogenated) portion in the molecule, which may contribute to its biological activities.
Carbonyl groups
Contains two carbonyl groups (C=O) at positions 7 and 9, which may play a role in its biological activities and reactivity.
Solubility
Likely to be soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) due to its nonpolar nature.
Stability
May be sensitive to light, heat, or acidic conditions, as is common with compounds containing aromatic rings and carbonyl groups.
Synthesis
The synthesis of this compound may involve multiple steps, including the formation of the benzo[a]heptalene core, followed by the introduction of methoxy groups and the dihydro functionality.
Analytical techniques
Techniques such as nuclear magnetic resonance (NMR), mass spectrometry (MS), and infrared (IR) spectroscopy can be used to analyze and confirm the structure of this compound.
Potential applications
Due to its biological activities, this compound may be explored for use in the development of new drugs targeting oxidative stress, inflammation, and cancer.
Safety and handling
As with any chemical compound, appropriate safety measures should be taken when handling 1,2,3,10-tetramethoxy-5,6-dihydrobenzo[a]heptalene-7,9-dione, including the use of personal protective equipment (PPE) and proper disposal methods.
Check Digit Verification of cas no
The CAS Registry Mumber 1850-57-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,5 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1850-57:
(6*1)+(5*8)+(4*5)+(3*0)+(2*5)+(1*7)=83
83 % 10 = 3
So 1850-57-3 is a valid CAS Registry Number.
1850-57-3Relevant articles and documents
Attempted oxidative deamination of N-deacetylcolchicinoids with 3,5- di(tert-butyl)-1,2-benzoquinone: Synthesis of 2h-1,4-benzoxazine-type adducts
Danieli, Bruno,Lesma, Giordano,Passarella, Daniele,Prosperi, Davide,Silvani, Alessandra,Bombardelli, Ezio
, p. 1502 - 1508 (1999)
In an attempt to use 3,5-di(tert-butyl)-1,2-benzoquinone for the oxidative deamination of N-deacetylcolchicine (4) and N- deacetylthiocolchicine (= N-deacetyl-10-demethoxy-10-(metbylthio)colchicine; 5) to give the corresponding ketones 2 and 3, the 2H-1,4-benzoxazine-type adducts 8/9 and 11/12, respectively, were formed instead, showing a new and unexpected behavior of Corey's reagent. The adducts were separated and spectroscopically characterized, and a plausible scheme of formation is reported.
Semisyntheses, X-Ray Crystal Structures and Tubulin-Binding Properties of 7-Oxodeacetamidocolchicine and 7-Oxodeacetamidoisocolchicine
Banwell, Martin G.,Peters, Steven C.,Greenwood, Richard J.,Mackay, Maureen F.,Hamel, Ernest,Lin, Chii M.
, p. 1577 - 1588 (2007/10/02)
Commercially available (-)-colchicine (1) has been converted, via deacetylcolchiceine (4), into a mixture of 7-oxodeacetamidocolchicine (2) and 7-oxodeacetamidoisocolchicine (3).The X-ray structures and tubulin-binding properties of these title ketones are described.
