185259-85-2 Usage
Uses
GR 46611is a 5-HT1D agonist.
Biological Activity
5-HT 1D receptor agonist. Blockade of GR 46611-induced hypothermia in the guinea pig provides a useful model with which to study the potency and duration of action of centrally acting 5-HT 1D receptor ligands.
Check Digit Verification of cas no
The CAS Registry Mumber 185259-85-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,2,5 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 185259-85:
(8*1)+(7*8)+(6*5)+(5*2)+(4*5)+(3*9)+(2*8)+(1*5)=172
172 % 10 = 2
So 185259-85-2 is a valid CAS Registry Number.
InChI:InChI=1/C23H27N3O2/c1-26(2)13-12-19-16-24-22-10-6-17(14-21(19)22)7-11-23(27)25-15-18-4-8-20(28-3)9-5-18/h4-11,14,16,24H,12-13,15H2,1-3H3,(H,25,27)/b11-7+
185259-85-2Relevant articles and documents
METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS
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Page/Page column 30, (2008/12/08)
The present invention relates to single and dual reporter luminescence assays utilizing reagents to quench an optical, e.g., an enzyme-mediated luminescence, reaction. In one embodiment of the invention, a reagent is added to an assay which selectively quenches a first enzyme-mediated luminescence reaction without affecting a subsequent distinct enzyme-mediated luminescent reaction(s). An assay kit containing one or more selective quench reagents, and compositions comprising the quench reagent(s), are also provided.
