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185426-14-6

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185426-14-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 185426-14-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,4,2 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 185426-14:
(8*1)+(7*8)+(6*5)+(5*4)+(4*2)+(3*6)+(2*1)+(1*4)=146
146 % 10 = 6
So 185426-14-6 is a valid CAS Registry Number.

185426-14-6Downstream Products

185426-14-6Relevant articles and documents

Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors

Chan, Grace Ka Yan,Chen, Huifen,Chen, Yong,Dimitrova, Yoana N.,Hu, Dennis X.,Huang, Haochu,Lee, Joanna Y.,Lim, Junghyun,McNamara, Erin,Moffat, John G.,Murthy, Aditya,Pang, Jodie,Patel, Snahel,Prangley, Madeleine S.,Salphati, Laurent,Schutt, Leah K.,Siu, Michael,Sneeringer, Christopher J.,Staben, Steven T.,Wallweber, Heidi Ackerly,Wang, Shumei,Wang, Yunli,Wu, Kai C.,Zhao, Wensheng

supporting information, (2021/12/02)

VPS34 is a class III phosphoinositide 3-kinase involved in endosomal trafficking and autophagosome formation. Inhibitors of VPS34 were believed to have value as anticancer agents, but genetic and pharmacological data suggest that sustained inhibition of V

Asymmetric synthesis of α-alkylated aldehydes using terminal epoxide-derived chiral enamines

Hodgson, David M.,Kaka, Naeem S.

supporting information; experimental part, p. 9958 - 9960 (2009/06/30)

(Chemical Equation Presented) Effective discrimination: Efficient lithium amide-induced terminal epoxide-enamine transformation provides the first enamines capable of generating α-alkylated aldehydes with high asymmetric induction by intermolecular nucleophilic substitution (see scheme).

Highly diastereoselective oxy-Michael additions of enantiopure δ-lactol anions to nitroalkenes: Asymmetric synthesis of 1,2-amino alcohols

Adderley, Nicola J.,Buchanan, David J.,Dixon, Darren J.,Laine, Dramane I.

, p. 4241 - 4244 (2007/10/03)

The "naked" alkoxide 1 of (S)-6-methyl-δ-lactol acts as an excellent chiral hydroxide equivalent in highly diastereoselective oxy-Michael additions to nitroalkenes (see scheme). The excellent stereoinduction arises from what becomes a superb protecting gr

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