185427-48-9Relevant articles and documents
Dehydrogenative Diboration of Alkynes Catalyzed by Ir/CO/tBuNC System
Lai, Qingheng,Ozerov, Oleg V.
, (2020/11/30)
Catalytic dehydrogenative diboration (DHDB) of alkyne with HBpin was achieved using [Ir(COD)Cl]2 and other related Ir precursors under CO atmosphere. The selectivity for DHDB over hydroboration was higher in less polar solvents and under higher
Synthesis of Polysubstituted Isoquinolines and Related Fused Pyridines from Alkenyl Boronic Esters via a Copper-Catalyzed Azidation/Aza-Wittig Condensation Sequence
Jayaram, Vankudoth,Sridhar, Tailor,Sharma, Gangavaram V. M.,Berrée, Fabienne,Carboni, Bertrand
, p. 843 - 853 (2018/01/28)
An efficient and straightforward synthesis of isoquinolines is reported from internal alkenyl boronic esters, easily prepared from the corresponding 1,2-bis(boronates), via a sequential copper-catalyzed azidation/aza-Wittig condensation. This synthetic method has been used to synthesize quinisocaine, a topical anesthetic used for the treatment of pain and pruritus, and further extended to thieno[2,3-c]pyridines by using 2-thiophenecarboxaldehyde as coupling partner in the first step.
Convenient synthesis of α,α-difluorinated carbonyl compounds from alkynes through a fluoro-deboronation process
Ramirez, Jesus,Fernandez, Elena
, p. 1698 - 1700 (2007/10/03)
Catalytic diboration of alkynes towards alkenyl diboronates provides suitable intermediates that can be converted into α-fluorinated and α,α-difluorinated carbonyl compounds via electrophilic fluorination with Selectfluor. Georg Thieme Verlag Stuttgart.
