18676-07-8 Usage
Description
Hispanolone, a natural steroid compound, is predominantly found in the bark of the Pygeum africanum tree. It exhibits anti-inflammatory, anti-androgenic, and anti-estrogenic properties, making it a versatile compound with potential applications in various medical and cosmetic fields.
Uses
Used in Traditional Medicine:
Hispanolone is used as a traditional medicine for treating benign prostatic hyperplasia (BPH) and related conditions. Its anti-inflammatory properties help reduce swelling and discomfort in the prostate, while its anti-androgenic properties inhibit the production of hormones that contribute to BPH.
Used in Hormonal Disorders:
Hispanolone is used as a hormone balancer for addressing hormonal disorders such as acne and baldness. Its anti-estrogenic properties help regulate hormone levels in the body, potentially alleviating symptoms associated with hormonal imbalances.
Used in Pharmaceutical Industry:
Hispanolone is used as a pharmaceutical compound for developing treatments targeting BPH and other hormone-related conditions. Its multifaceted properties make it a promising candidate for drug development, offering potential therapeutic benefits for patients suffering from these conditions.
Used in Cosmetic Industry:
Hispanolone is used as an ingredient in cosmetic products for addressing acne and other skin conditions. Its anti-inflammatory and hormone-regulating properties may help improve skin health and reduce the appearance of acne.
Check Digit Verification of cas no
The CAS Registry Mumber 18676-07-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,7 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18676-07:
(7*1)+(6*8)+(5*6)+(4*7)+(3*6)+(2*0)+(1*7)=138
138 % 10 = 8
So 18676-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O3/c1-14-16(21)12-17-18(2,3)8-5-9-19(17,4)20(14,22)10-6-15-7-11-23-13-15/h7,11,13-14,17,22H,5-6,8-10,12H2,1-4H3/t14-,17+,19+,20-/m1/s1
18676-07-8Relevant articles and documents
PREHISPANOLONE, A LABDANE DITERPENE FROM LEONURUS HETEROPHYLLUS
Hon, Po-Ming,Lee, Chi-Ming,Shang, Hong-Sheng,Cui, Yu-Xin,Wong, Henry N. C.,Chang, Hson-Mou
, p. 354 - 356 (1991)
A new labdane diterpene, prehispanolone, has been isolated from Leonurus heterophyllus.Its structure, 9α,13R;15,16-diepoxylabdan-14-en-7-one, was established by spectroscopic means as well as by examination of its derivatives.
Total syntheses of naturally occurring molecules possessing 1,7- dioxaspiro[4.4]nonane skeletons
Wong, Henry N. C.
, p. 1757 - 1765 (2007/10/03)
The syntheses of several naturally occurring molecules, namely prehispanolone, sphydrofuran, secosyrins, and syringolides are reviewed. Interestingly, these compounds are all structurally related, possessing a 1,7-dioxaspiro[4.4]nonane framework. The pivotal step in these synthetic endeavors involves the peracid oxidation of substituted 2- trimethylsilylfurans to but-2-en-4-olides. A subsequent intramolecular Michael addition procedure was also essential in the construction of the spiro skeleton. Two significant issues concerning regioselectivity and stereoselectivity are also addressed.
