18677-43-5

• 

• Basic information

  1. Product Name: 2,4-DIMETHOXYPYRIDINE
  2. Synonyms: 2,4-DIMETHOXYPYRIDINE
  3. CAS NO:18677-43-5
  4. Molecular Formula: C₇H₉NO₂
  5. Molecular Weight: 139.15
  6. EINECS: 219-563-0
  7. Product Categories: Pyridines
  8. Mol File: 18677-43-5.mol
  9. Article Data: 6

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: 201.4 °C at 760 mmHg
  3. Flash Point: 72.4 °C
  4. Appearance: /
  5. Density: 1.064 g/cm³
  6. Vapor Pressure: 1.82mmHg at 25°C
  7. Refractive Index: 1.427
  8. Storage Temp.: Inert atmosphere,Room Temperature
  9. Solubility: N/A
  10. CAS DataBase Reference: 2,4-DIMETHOXYPYRIDINE(CAS DataBase Reference)
  11. NIST Chemistry Reference: 2,4-DIMETHOXYPYRIDINE(18677-43-5)
  12. EPA Substance Registry System: 2,4-DIMETHOXYPYRIDINE(18677-43-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 18677-43-5(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
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• Article

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18677-43-5 Usage

General Description

2,4-Dimethoxypyridine is a chemical compound with the molecular formula C7H9NO2. It is a derivative of pyridine, a six-membered heterocyclic ring containing five carbon atoms and one nitrogen atom. The compound is composed of a pyridine ring with two methoxy (CH3O-) groups attached at the 2 and 4 positions. 2,4-Dimethoxypyridine is used in various organic synthesis reactions, including as a building block in the production of pharmaceuticals and agrochemicals. It has also been studied for its potential use as a ligand in catalytic reactions. The compound is flammable and should be handled and stored with appropriate caution.

Check Digit Verification of cas no

The CAS Registry Mumber 18677-43-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,7 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18677-43:
(7*1)+(6*8)+(5*6)+(4*7)+(3*7)+(2*4)+(1*3)=145
145 % 10 = 5
So 18677-43-5 is a valid CAS Registry Number.

InChI:InChI=1/C7H12O/c1-2-3-4-5-6-7-8/h5-7H,2-4H2,1H3/b6-5+

18677-43-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	2,4-Dimethoxypyridine

1.2 Other means of identification

Product number	-
Other names	Pyridine,2,4-dimethoxy

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:18677-43-5 SDS

18677-43-5Upstream product

• 17228-69-2 2-chloro-4-methoxy-pyridine 
• 124-41-4 sodium methylate 
• 1124-33-0 4-nitraminopyridine N-oxide 
• 2408-70-0 2,4,6-tribromopyridine 
• 96245-98-6 2,3-dibromo-4-methoxypyridine 
• 2402-91-7 2,3,4-tribromopyridine 
• 626-03-9 3-deazauracil 
• 186581-53-3 diazomethane 
• 74-88-4 methyl iodide 
• 96246-00-3 3-bromo-2,4-dimethoxypyridine 
• 276251-83-3 2-bromo-4,6-dimethoxypyridine 
• 26452-80-2 2,4-dichloropyridine 

18677-43-5Downstream Products

• 626-03-9 3-deazauracil 
• 52606-07-2 5-bromo-2,4-dimethoxypyridine 
• 96246-00-3 3-bromo-2,4-dimethoxypyridine 

18677-43-5Relevant articles and documents

A convenient synthesis of gimeracil

Li, Xiao-Lin,Zhu, Hao-Ting,Zhan, Li,Liu, Ting,Cheng, Guang,Liu, Ning,Yu, Shan-Bao,Li, Hui,Luo, Yu,Yang, Fan,Tang, Jie

, p. 33 - 34 (2018/02/28)

A practical three-step synthetic approach to gimeracil in a 68% overall yield is described, using 2,4-dimethoxypyridine as the starting material with 3,5-dichloro-2,4-dimethoxypyridine and 3,5-dichloro-2,4-dihydroxypyridine as intermediates. The advantages of this procedure include short reaction steps, simple operation and good yield.

ANTI-FIBROTIC PYRIDINONES

-

Paragraph 0883-0884, (2014/04/17)

Disclosed are pyridinone compounds, method for preparing these compounds, and methods for treating fibrotic disorders.

NOVEL PYRIDINONE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2-RECEPTORS

-

Page/Page column 114, (2010/10/20)

The present invention relates to novel compounds, in particular novel pyridinone derivat ives according to Formula (I) X R1 N Y (I) R2 R3 wherein all radicals are defined in the application. The compounds according to the invention are positive allosteric modulators of metabotropic receptors-subt ype 2 ("mGluR2") which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved. "

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