18732-58-6Relevant articles and documents
Rapid and efficient protocol for Willgerodt–Kindler’s thioacetamides catalyzed by sulfated polyborate
Rekunge, Deelip S.,Khatri, Chetan K.,Chaturbhuj, Ganesh U.
, p. 2091 - 2095 (2017/10/06)
Abstract: A simple and efficient method for the synthesis of one-pot, three-component thioacetamides via Willgerodt–Kindler reaction was developed using a sulfated polyborate catalyst. The method described the reaction of ketones, sulfur, and secondary am
Decarboxylative thioamidation of arylacetic and cinnamic acids: A new approach to thioamides
Guntreddi, Tirumaleswararao,Vanjari, Rajeshwer,Singh, Krishna Nand
supporting information, p. 3624 - 3627 (2014/08/05)
A new decarboxylative strategy has been developed for the synthesis of thioamides via a three-component reaction involving arylacetic or cinnamic acids, amines and elemental sulfur powder, without the need of a transition metal and an external oxidant.
Thionation of amides using a solid-supported P2S5 reagent under microwave irradiation
Lagiakos, Helen Rachel,Walker, Ashley,Aguilar, Marie-Isabel,Perlmutter, Patrick
experimental part, p. 5131 - 5132 (2011/10/12)
In this Letter, we describe an improved method for the thionation of amides. Using a solid-supported P2S5 reagent, heating under microwave irradiation furnished thioamides in good to excellent yields, with a significantly reduced reaction time compared with that achieved under conventional heating. Furthermore, a change of solvent from that described in the literature enabled a simplified work-up and purification of the products.