18744-04-2Relevant articles and documents
Synthesis of 5-acetyl derivatives of alkyl 2-furoates and 3-(2-furyl)acrylates
Kuticheva,Pevzner,Petrov
, p. 424 - 427 (2015)
Methyl 5-acetyl-2-furoate has been prepared via oxidation of 5-(1-hydroxyethyl)-2-furoate with the Jones reagent. In turn, the starting compound has been synthesized via sequential chloroethylation of ethyl 2-furoate, substitution of chlorine with acetoxy group, and methanolysis of the acetate in presence of sodium methylate. The vinylog 2-furoate has been obtained as the major product via acetylation of ethyl 3-(2-furyl)-acrylate with acetic anhydride in the presence of magnesium perchlorate.