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19163-24-7

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  • BEST PRICE/5-Phenylthiophene-2-carboxylic acid CAS NO.19163-24-7

    Cas No: 19163-24-7

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19163-24-7 Usage

Description

5-Phenylthiophene-2-carboxylic acid is a chemical compound with the molecular formula C11H8O2S. It is a carboxylic acid derivative of phenylthiophene, a heterocyclic compound that features a thiophene ring fused with a phenyl group. Characterized by its aromatic and electron-rich properties, this compound serves as a valuable building block in organic synthesis and material science, with potential pharmaceutical applications and contributions to the development of innovative drugs.

Uses

Used in Organic Synthesis:
5-Phenylthiophene-2-carboxylic acid is utilized as a key intermediate in the synthesis of various organic molecules. Its unique structure and reactivity make it a versatile component in the creation of complex organic compounds for a range of applications.
Used in Material Science:
In the field of material science, 5-Phenylthiophene-2-carboxylic acid is employed as a component in the development of new materials. Its electron-rich nature and aromaticity contribute to the properties of these materials, enhancing their performance in specific applications.
Used in Pharmaceutical Development:
5-Phenylthiophene-2-carboxylic acid is used as a precursor in the pharmaceutical industry for the development of new drugs. Its chemical properties allow it to be modified and incorporated into drug molecules, potentially leading to the discovery of novel therapeutic agents.
Used in Research and Development:
In academic and industrial research settings, 5-Phenylthiophene-2-carboxylic acid is used as a model compound to study the properties and reactions of heterocyclic compounds. This aids in understanding their behavior and potential uses in various chemical and biological processes.
Overall, 5-Phenylthiophene-2-carboxylic acid is a multifaceted chemical entity with applications that span across organic synthesis, material science, pharmaceuticals, and research, highlighting its significance in the advancement of scientific knowledge and technological innovation.

Check Digit Verification of cas no

The CAS Registry Mumber 19163-24-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,6 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 19163-24:
(7*1)+(6*9)+(5*1)+(4*6)+(3*3)+(2*2)+(1*4)=107
107 % 10 = 7
So 19163-24-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3N2/c9-8(10,11)6-1-2-7(3-4-12)13-5-6/h1-2,5H,3H2

19163-24-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Phenyl-2-thiophenecarboxylic acid

1.2 Other means of identification

Product number -
Other names 5-Phenylthiophene-2-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19163-24-7 SDS

19163-24-7Relevant articles and documents

Aqueous-Phase Chemistry of η3-Allylpalladium(II) Complexes with Sulfonated N-Heterocyclic Carbene Ligands: Solvent Effects in the Protolysis of Pd-C Bonds and Suzuki-Miyaura Reactions

Asensio, Juan M.,Andrés, Román,Gómez-Sal, Pilar,De Jesús, Ernesto

, p. 4191 - 4201 (2017)

The synthesis of water-soluble η3-allyl Pd(II) complexes containing sulfonated N-heterocyclic carbene (NHC) ligands of general formula [Pd(NHC)n(η3-allyl)Cl2-n] is reported (n = 1 (1) or 2 (8)). Monocarbene complexes were obtained with the most sterically hindered NHC ligands, and biscarbenes with the less sterically hindered NHCs. The behavior of the isolated complexes in water under acidic, neutral, or alkaline conditions has been studied. The complexes are rather stable in water under neutral or alkaline conditions, although displacement of the chlorido ligand by water or hydroxide occurs under these conditions. In acidic media, Pd-NHC bonds are protolysed, and it is especially noteworthy that this protolysis occurs preferentially to that of the Pd-allyl bonds in the case of the complexes with the less-sterically hindered NHC ligands. This behavior contrasts with that observed in dimethyl sulfoxide (dmso), where the Pd-allyl bonds are selectively broken upon treatment with Br?nsted acids. In addition, Pd-NHC bond breaking was promoted by the addition of a strong σ-donor ligand such as cyanide. Complex 1a is an active catalyst for the Suzuki-Miyaura cross-coupling of water-soluble aryl chlorides in neat water under moderate conditions (typically, 0.5 mol % Pd and 60 °C).

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Chakrabarti,Chapman

, p. 914,918,919 (1970)

-

Redox-Neutral Photocatalytic C?H Carboxylation of Arenes and Styrenes with CO2

Bergonzini, Giulia,Brandt, Peter,Fricke, Florian,Johansson, Magnus J.,K?nig, Burkhard,Schmalzbauer, Matthias,Svejstrup, Thomas D.

supporting information, p. 2658 - 2672 (2020/10/07)

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Furan- and thiophene-2-carbonyl amino acid derivatives activate hypoxia-inducible factor via inhibition of factor inhibiting hypoxia-inducible factor-1

Kawaguchi, Shin-ichi,Gonda, Yuhei,Yamamoto, Takuya,Sato, Yuki,Shinohara, Hiroyuki,Kobiki, Yohsuke,Ichimura, Atsuhiko,Dan, Takashi,Sonoda, Motohiro,Miyata, Toshio,Ogawa, Akiya,Tsujita, Tadayuki

, (2018/04/17)

Induction of a series of anti-hypoxic proteins protects cells during exposure to hypoxic conditions. Hypoxia-inducible factor-α (HIF-α) is a major transcription factor that orchestrates this protective effect. To activate HIF exogenously, without exposing

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