19164-83-1Relevant articles and documents
Bredow et al.
, p. 543,548,553 (1970)
Synthesis, X-ray structure and binding properties of molecular clips based on dimethylpropanediurea
Jansen, Rob J.,Rowan, Alan E.,De Gelder, Rene,Scheeren, Hans W.,Nolte, Roeland J. M.
, p. 121 - 122 (1998)
New concave host molecules show strong noncovalent binding of hydroxybenzene derivatives by an induced fit mechanism (Ka up to 3.4 × 106 dm3 mol-1).
Overriding Intrinsic Reactivity in Aliphatic C?H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrates
Heilmann, Michael,Knezevic, Melina,Piccini, Giovanni Maria,Tiefenbacher, Konrad
supporting information, p. 12387 - 12391 (2020/07/04)
The site-selective C?H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well-explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.
Composition for treatment of pathogens that are resistant to tetracyclines
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Paragraph 0105-0106, (2014/08/19)
The invention relates to compounds and pharmaceutical compositions useful in combination with tetracyclines in the treatment of bacterial infections caused by Gram-positive and Gram-negative pathogens, with particular efficacy in tetracycline resistant st
