191864-24-1 Usage
Description
Zolmitriptan Related Compound D (20 mg) ((S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate) is a derivative of Zolmitriptan (Z639000), which is a Serotonin 5HT1D-receptor agonist. It is a chemical compound with a specific molecular structure that has potential applications in various industries due to its interaction with the serotonin receptor.
Uses
Used in Pharmaceutical Industry:
Zolmitriptan Related Compound D (20 mg) ((S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate) is used as a pharmaceutical compound for its agonistic action on the Serotonin 5HT1D-receptor. This makes it a potential candidate for the development of medications targeting conditions that involve the serotonin system, such as migraines and other headaches.
Used in Research and Development:
In the field of research and development, Zolmitriptan Related Compound D (20 mg) ((S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate) can be utilized as a research tool to study the mechanisms of serotonin receptor agonists and their effects on various physiological processes. This can lead to a better understanding of the serotonin system and the development of new therapeutic strategies for related conditions.
Used in Drug Synthesis:
Zolmitriptan Related Compound D (20 mg) ((S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate) may also be used in the synthesis of other related compounds with potential therapeutic applications. Its structural features can be modified to create new molecules with improved pharmacological properties or reduced side effects, contributing to the development of novel drugs for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 191864-24-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,8,6 and 4 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 191864-24:
(8*1)+(7*9)+(6*1)+(5*8)+(4*6)+(3*4)+(2*2)+(1*4)=161
161 % 10 = 1
So 191864-24-1 is a valid CAS Registry Number.
191864-24-1Relevant articles and documents
Synthesis of zolmitriptan and related substances
Vujjini, Satish Kumar,Mothukuri, Vivekananda Reddy,Islam, Aminul,Bandichhor, Rakeshwar,Kagga, Mukkanti,Malakondaiah, Golla China
, p. 3294 - 3306 (2013/10/01)
Efficient and cost-effective synthesis of Zolmitriptan 1 employing Japp-Klingemann reaction and a new robust purification strategy is described.
PROCESS FOR PREPARING ZOLMITRIPTAN COMPOUNDS
-
Page 16-17, (2008/06/13)
In particular, zolmitriptan or a pharmaceutically acceptable salt thereof, which includes a) Preparation of the diazonium salt of the aniline hydrochloride (II); followed by reduction and acidification to give hydrazine (III); b) In situ Reaction of the hydrazine hydrochloride (III) with ?-keto-?-valerolactone, to give the hydrazone (IV); c) Fischer indole synthesis of the hydrazone (IV), to give the pyranoindolone of formula (V); d) Transesterification of the pyranoindolone (V) to provide the compound (VI), in which R means a straight or branched C1-C4 alkyl; e) Conversion of the hydroxyl group of the compound (VI) into dimethylamino to give the indolecarboxylate (VII), in which R means a straight or branched C1-C4 alkyl; f) Saponification of the 2-carboalkoxy group of the compound (VII), to provide indolecarboxylic acid (VIII); g) Decarboxylation of the indolecarboxylic acid (VIII), to provide zolmitriptan and, eventually, to provide a pharmaceutically acceptable salt thereof.