192725-39-6

• 

• Basic information

  1. Product Name: Lopinavir Metabolite M-1
  2. Synonyms: (aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-d;Lopinavir Metabolite M-1;(aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami- de;(aS)-N-[(1S,3S,4S)-4-[[(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-a-(1-methylethyl)-2,4-dioxo-1(2H)-Pyrimidineacetami-de;(αS)-N-[(1S,3S,4S)-4-[[(2,6-DiMethylphenoxy)acetyl]aMino]-3-hydroxy-5-phenyl-1-(phenylMethyl)pentyl]tetrahydro-α-(1-Methylethyl)-2,4-dioxo-1(2H)-pyriMidineacetaMi- de
  3. CAS NO:192725-39-6
  4. Molecular Formula: C₃₇H₄₆N₄O₆
  5. Molecular Weight: 642.792
  6. EINECS: N/A
  7. Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Non-nucleoside Reverse Transcriptase;Pharmaceuticals
  8. Mol File: 192725-39-6.mol
  9. Article Data: 3

• Chemical Properties

  1. Melting Point: 106-108°C
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: 1.582
  7. Storage Temp.: -20°C Freezer
  8. Solubility: Chloroform (Slightly), Methanol (Slightly)
  9. CAS DataBase Reference: Lopinavir Metabolite M-1(CAS DataBase Reference)
  10. NIST Chemistry Reference: Lopinavir Metabolite M-1(192725-39-6)
  11. EPA Substance Registry System: Lopinavir Metabolite M-1(192725-39-6)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 192725-39-6(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

192725-39-6 Suppliers

Recommended suppliersmore

• Product
• FOB Price
• Min.Order
• Supply Ability
• Supplier
• Contact Supplier

• Lopinavir Metabolite M-1

  Cas No: 192725-39-6

• No Data

• No Data

• No Data

• BOC Sciences
• Contact Supplier

• Lopinavir Metabolite M-1

  Cas No: 192725-39-6

• No Data

• 1 Milligram

• 10 Milligram /Week

• Beijing Top Science biological technology co., LTD
• Contact Supplier

• Lopinavir Metabolite M-1

  Cas No: 192725-39-6

• No Data

• No Data

• No Data

• Finetech Industry Limited
• Contact Supplier

• Lopinavir Metabolite M1

  Cas No: 192725-39-6

• No Data

• No Data

• No Data

• Topbatt Chemical Co., Ltd.
• Contact Supplier

• Lopinavir Metabolite M1

  Cas No: 192725-39-6

• No Data

• No Data

• No Data

• Shenzhen Sumshine Biotech Co., Ltd.
• Contact Supplier

• Lopinavir Metabolite M1

  Cas No: 192725-39-6

• No Data

• No Data

• No Data

• NovaChemistry
• Contact Supplier

192725-39-6 Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 192725-39-6 differently. You can refer to the following data:
1. A major metabolite of Lopinavir (L469480) . It is a COVID19-related research product.
2. A major metabolite of Lopinavir (L469480) .

Check Digit Verification of cas no

The CAS Registry Mumber 192725-39-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,7,2 and 5 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 192725-39:
(8*1)+(7*9)+(6*2)+(5*7)+(4*2)+(3*5)+(2*3)+(1*9)=156
156 % 10 = 6
So 192725-39-6 is a valid CAS Registry Number.

InChI:InChI=1/C37H46N4O6/c1-24(2)34(41-19-18-32(43)40-37(41)46)36(45)38-29(20-27-14-7-5-8-15-27)22-31(42)30(21-28-16-9-6-10-17-28)39-33(44)23-47-35-25(3)12-11-13-26(35)4/h5-17,24,29-31,34,42H,18-23H2,1-4H3,(H,38,45)(H,39,44)(H,40,43,46)/t29?,30?,31-,34-/m0/s1

192725-39-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	Lopinavir Metabolite M-1

1.2 Other means of identification

Product number	-
Other names	(2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxy-5-(2S-(1-tetrahydropyrimid-2,4-dionyl)-3-methyl-butanoyl)amino-1,6-diphenylhexane

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:192725-39-6 SDS

192725-39-6Upstream product

• 192725-88-5 (S)-2-(2,4-dioxotetrahydropyrimidin-1-yl)-3-methylbutyric acid tert-butyl ester 
• 13335-71-2 2-(2,6-dimethylphenoxy)acetic acid 
• 13211-31-9 tert-butyl L-valinate 
• 192725-89-6 (S)-2-(2,4-dioxotetrahydropyrimidin-1-yl)-3-methylbutyric acid 
• 192725-49-8 (2S,3S,5S)-2-(2,6-dimethylphenoxyacetyl)amino-3-hydroxy-5-amino-1,6-diphenylhexane 
• 192725-87-4 N-(2-carboxamido)ethyl-L-valine t-butyl ester 
• 192725-86-3 N-(2-carbomethoxy)ethyl-L-valine t-butyl ester 

192725-39-6Downstream Products

• 221553-72-6 (S)-N-{(1S,3S,4S)-1-Benzyl-4-[2-(2,6-dimethyl-phenoxy)-acetylamino]-3-hydroxy-5-phenyl-pentyl}-2-(4-hydroxy-2-oxo-tetrahydro-pyrimidin-1-yl)-3-methyl-butyramide 

192725-39-6Relevant articles and documents

Novel lopinavir analogues incorporating heterocyclic replacements of six-member cyclic urea - Synthesis and structure-activity relationships

Sham, Hing L.,Betebenner, David A.,Rosenbrook, William,Herrin, Thomas,Saldivar, Ayda,Vasavanonda, Sudthida,Plattner, Jacob J.,Norbeck, Daniel W.

, p. 2643 - 2645 (2007/10/03)

The HIV protease inhibitor ABT-378 (lopinavir) has a six-member cyclic urea in the P-2 position. A series of analogues in which the six-member cyclic urea is replaced by various heterocycles was synthesized and the structure-activity relationships explored.

Synthesis and antiviral activities of the major metabolites of the HIV protease inhibitor ABT-378 (Lopinavir)

Sham, Hing L,Betebenner, David A,Herrin, Thomas,Kumar, Gondi,Saldivar, Ayda,Vasavanonda, Sudthida,Molla, Akhter,Kempf, Dale J,Plattner, Jacob J,Norbeck, Daniel W

, p. 1351 - 1353 (2007/10/03)

The HIV protease inhibitor ABT-378 (Lopinavir) is metabolized rapidly and extensively by CYP-3A4 catalyzed oxidation. Three of the major metabolites identified were synthesized and their antiviral (HIV) activities determined.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 192725-39-6 Lopinavir Metabolite M-1

Send

Send

Metric Ton KG G Pound L ML

Send

Send