19394-61-7Relevant articles and documents
Organophosphine-free copper-catalyzed isothiocyanation of amines with sodium bromodifluoroacetate and sulfur
Feng, Wei,Zhang, Xing-Guo
supporting information, p. 1144 - 1147 (2019/01/28)
A copper-catalyzed isothiocyanation of amines with sodium bromodifluoroacetate and sulfur in the absence of organophosphine has been established. This approach represents a simple and efficient one-pot synthesis of isothiocyanates, and features excellent functional group tolerance and the use of a cheap, safe and odorless sulfur source. Moreover, this process could directly provide isothiocyanate analogous bioactive molecules, thiocarbonyl-containing pesticides and facile construction of benzoxazole and benzimidazole frames.
Isothiocyanation of amines using the Langlois reagent
Liao, Yan-Yan,Deng, Jian-Chao,Ke, Yan-Ping,Zhong, Xiao-Lin,Xu, Li,Tang, Ri-Yuan,Zheng, Wenxu
supporting information, p. 6073 - 6076 (2017/07/10)
The Langlois reagent was found to be effective for the isothiocyanation of primary amines in the presence of copper iodide and diethyl phosphonate.
Diversity-orientated synthesis of 3,5-bis(arylamino)pyrazoles
Degorce, Sébastien,Jung, Frédéric H.,Harris, Craig S.,Koza, Patrice,Lecoq, Jonathan,Stevenin, Arnaud
supporting information; experimental part, p. 6719 - 6722 (2012/01/05)
The synthesis of differentially-substituted 3,5-bis(arylamino)pyrazoles has not yet been documented. During our investigation, we managed to develop a novel, entirely combinatorial synthesis of 3,5-bis(arylamino)pyrazoles relying on a simple one-pot two-step operation.
