19433-01-3Relevant articles and documents
Synthesis and QSAR studies on hypotensive 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines
Saxena, Anil K.,Rao, Jyoti,Chakrabarty, Ruchika,Saxena, Mridula,Srimal
, p. 1708 - 1712 (2007/10/03)
A series of 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines has been synthesized and evaluated for hypotensive activity. The QSAR studies indicate that resonance and hydrophobic parameters of the aryl substituents are important
Synthesis of N-heterocyclics as Potential CNS/CVS Agents
Rao, Jyoti,Saxena, Anil K.,Saxena, R. M.,Singh, H. K.,Kar, K.,Srimal, R. C.
, p. 761 - 765 (2007/10/02)
A number of N-heterocyclics (6-13, 19-21) have been synthesized by the condensation of γ-chloropropylaryl sulphides and sulphones (3-5 and 18) with appropriate nitrogen heterocyclics.The 4-aminophenyl derivatives in case of su