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19434-65-2

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19434-65-2 Usage

General Description

3-Chloropropanal, also known as 3-chloropropanaldehyde, is a chemical compound with the formula C3H5ClO. It is a colorless to pale yellow liquid with a pungent odor and is slightly soluble in water. 3-Chloropropanal is used as an intermediate in the production of pharmaceuticals, pesticides, and other organic compounds. It is also used in the synthesis of various chemical compounds and as a reagent in organic chemistry reactions. 3-Chloropropanal is known to be an irritant to the skin, eyes, and respiratory system and should be handled with caution. It is important to follow safety precautions when working with this chemical to minimize the risk of exposure and adverse health effects.

Check Digit Verification of cas no

The CAS Registry Mumber 19434-65-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,4,3 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 19434-65:
(7*1)+(6*9)+(5*4)+(4*3)+(3*4)+(2*6)+(1*5)=122
122 % 10 = 2
So 19434-65-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H5ClO/c4-2-1-3-5/h3H,1-2H2

19434-65-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-chloropropanal

1.2 Other means of identification

Product number -
Other names Propanal, 3-chloro-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19434-65-2 SDS

19434-65-2Related news

IR-induced photorotamerization of propanal and 3-chloropropanal (cas 19434-65-2) in low-temperature matrices. Ab initio optimization of conformer geometries, and calculation of torsional barrier heights08/17/2019

Propanal and 3-chloropropanal have been studied in solid Ar and N2 matrices. A fast IR-induced cis → gauche process was found for propanal, whereas the reverse process occurred in the dark upon warming the matrices. A very fast process was found for 3-chloropropanal in Ar; in N2 it was 60 times...detailed

19434-65-2Relevant articles and documents

New series of double-modified colchicine derivatives: Synthesis, cytotoxic effect and molecular docking

Aminpour, Maral,Huczyn?ski, Adam,Krzywik, Julia,Maj, Ewa,Mozga, Witold,Tuszyn?ski, Jack A.,Wietrzyk, Joanna

, (2020)

Colchicine is a well-known anticancer compound showing antimitotic effect on cells. Its high cytotoxic activity against different cancer cell lines has been demonstrated many times. In this paper we report the syntheses and spectroscopic analyses of novel colchicine derivatives obtained by structural modifications at C7 (carbon-nitrogen single bond) and C10 (methylamino group) positions. All the obtained compounds have been tested in vitro to determine their cytotoxicity toward A549, MCF-7, LoVo, LoVo/DX, and BALB/3T3 cell lines. The majority of obtained derivatives exhibited higher cytotoxicity than colchicine, doxorubicin and cisplatin against the tested cancerous cell lines. Additionally, most of the presented derivatives were able to overcome the resistance of LoVo/DX cells. Additionally, their mode of binding to β-tubulin was evaluated in silico. Molecular docking studies showed that apart from the initial amides 1 and 2, compound 14, which had the best antiproliferative activity (IC50 = 0.1–1.6 nM), stood out also in terms of its predicted binding energy and probably binds best into the active site of βI-tubulin isotype.

ANTIMICROBIAL COMPOSITIONS, METHODS OF MAKING, AND METHODS OF USE

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Paragraph 0011; 0013, (2019/03/08)

The invention provides a protected antimicrobial compound and methods of using the same.

PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF MITOCHONDRIAL DISORDERS

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Page/Page column 50, (2017/07/29)

The present invention provides novel cell-permeable carboxylic acid-based metabolites and cell permeable precursors thereof aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates fr

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