194938-88-0

• 

• Basic information

  1. Product Name: Methyl 2,6-difluoro-4-hydroxybenzoate
  2. Synonyms: Methyl 2,6-difluoro-4-hydroxybenzoate
  3. CAS NO:194938-88-0
  4. Molecular Formula: C8H6F2O3
  5. Molecular Weight: 188.1282464
  6. EINECS: -0
  7. Product Categories: N/A
  8. Mol File: 194938-88-0.mol
  9. Article Data: 10

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: /
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: 2-8°C
  8. Solubility: N/A
  9. CAS DataBase Reference: Methyl 2,6-difluoro-4-hydroxybenzoate(CAS DataBase Reference)
  10. NIST Chemistry Reference: Methyl 2,6-difluoro-4-hydroxybenzoate(194938-88-0)
  11. EPA Substance Registry System: Methyl 2,6-difluoro-4-hydroxybenzoate(194938-88-0)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 194938-88-0(Hazardous Substances Data)

• Suppliers
• Usage
• SDS
• Upstream product
• Downstream Products
• Article

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• Methyl 2,6-difluoro-4-hydroxybenzoate

  Cas No: 194938-88-0

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• 10 Milligram

• Amadis Chemical Co., Ltd.
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• 2,6-Difluoro-4-hydroxybenzoic acid methyl ester

  Cas No: 194938-88-0

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• Dayang Chem (Hangzhou) Co.,Ltd.
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• Benzoic acid, 2,6-difluoro-4-hydroxy-, methyl ester

  Cas No: 194938-88-0

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• 1 Gram

• 100 Metric Ton/Month

• Wuhan Kemi-Works Chemical Co., Ltd
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• Methyl 2,6-difluoro-4-hydroxybenzoate cas no. 194938-88-0 98%

  Cas No: 194938-88-0

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• Win-Win chemical Co.Ltd
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• Benzoic acid, 2,6-difluoro-4-hydroxy-, methyl ester

  Cas No: 194938-88-0

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• Kono Chem Co.,Ltd
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• Methyl 2,6-difluoro-4-hydroxybenzoate manufacture

  Cas No: 194938-88-0

• USD $ 1.0-9999.0 / Kilogram

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• Changzhou Pesan Chemical Co.,Ltd
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194938-88-0 Usage

Description

Methyl 2,6-difluoro-4-hydroxybenzoate is a chemical compound derived from salicylic acid, characterized by the presence of two fluorine atoms and a hydroxy group in its molecular structure. It is known for its antimicrobial, anti-inflammatory, and analgesic properties, making it a versatile ingredient in various applications.

Uses

Used in Pharmaceutical Industry:
Methyl 2,6-difluoro-4-hydroxybenzoate is used as a preservative and stabilizer in pharmaceutical formulations for its antimicrobial properties, ensuring the stability and safety of the products.
Used in Cosmetics and Personal Care Products:
Methyl 2,6-difluoro-4-hydroxybenzoate is used as a preservative in cosmetics and personal care products to prevent microbial contamination and extend the shelf life of these products.
Used in Topical Medications:
Methyl 2,6-difluoro-4-hydroxybenzoate is used as an active ingredient in topical medications due to its anti-inflammatory and analgesic properties, providing relief from pain and inflammation.
Used in Skincare Formulations:
Methyl 2,6-difluoro-4-hydroxybenzoate is used in skincare formulations for its antimicrobial and anti-inflammatory properties, promoting skin health and preventing infections.
It is important to handle and store Methyl 2,6-difluoro-4-hydroxybenzoate with care, as it can be harmful if ingested or comes into contact with the skin or eyes.

Check Digit Verification of cas no

The CAS Registry Mumber 194938-88-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,9,3 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 194938-88:
(8*1)+(7*9)+(6*4)+(5*9)+(4*3)+(3*8)+(2*8)+(1*8)=200
200 % 10 = 0
So 194938-88-0 is a valid CAS Registry Number.

194938-88-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	Methyl 2,6-difluoro-4-hydroxybenzoate

1.2 Other means of identification

Product number	-
Other names	Benzoic acid,2,6-difluoro-4-hydroxy-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:194938-88-0 SDS

194938-88-0Upstream product

• 123843-57-2 2,6-difluoro-4-hydroxybenzonitrile 
• 67-56-1 methanol 
• 214917-68-7 2,6-difluoro-4-hydroxybenzoic acid 
• 84937-82-6 methyl 2,6-difluoro-4-methoxybenzoate 

194938-88-0Downstream Products

194938-88-0Relevant articles and documents

TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY

-

, (2021/01/22)

The present invention relates to quinazolinones and related compounds which degrade PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

Lasalle, Manuel,Hoguet, Vanessa,Hennuyer, Nathalie,Leroux, Florence,Piveteau, Catherine,Belloy, Lo?c,Lestavel, Sophie,Vallez, Emmanuelle,Dorchies, Emilie,Duplan, Isabelle,Sevin, Emmanuel,Culot, Maxime,Gosselet, Fabien,Boulahjar, Rajaa,Herledan, Adrien,Staels, Bart,Deprez, Benoit,Tailleux, Anne,Charton, Julie

, p. 4185 - 4211 (2017/06/05)

The role of the G-protein-coupled bile acid receptor TGR5 in various organs, tissues, and cell types, specifically in intestinal endocrine L-cells and brown adipose tissue, has made it a promising therapeutical target in several diseases, especially type-2 diabetes and metabolic syndrome. However, recent studies have shown deleterious on-target effects of systemic TGR5 agonists. To avoid these systemic effects while stimulating glucagon-like peptide-1 (GLP-1) secreting enteroendocrine L-cells, we have designed TGR5 agonists with low intestinal permeability. In this article, we describe their synthesis, characterization, and biological evaluation. Among them, compound 24 is a potent GLP-1 secretagogue, has low effect on gallbladder volume, and improves glucose homeostasis in a preclinical murine model of diet-induced obesity and insulin resistance, making the proof of concept of the potential of topical intestinal TGR5 agonists as therapeutic agents in type-2 diabetes.

AROMATASE INHIBITOR

-

Page/Page column 114, (2011/04/14)

There is provided a compound of formula (I) wherein Z is selected from N and CR22, wherein R22 is H or a bond with D, wherein D is selected from a bond, C=O, and linear or branched hydrocarbon groups having a carbon chain of from 1 t

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