19543-85-2Relevant articles and documents
Pure organic room-temperature phosphorescent material based on thiochromanone derivative as well as preparation method and application of pure organic room-temperature phosphorescent material
-
Paragraph 0040; 0044-0046, (2021/04/21)
The embodiment of the invention discloses a pure organic room-temperature phosphorescent material based on a thiochromanone derivative as well as a preparation method and application of the pure organic room-temperature phosphorescent material. The organi
Synthesis and anti cervical cancer activity of novel 5H-thiochromeno [4,3-d]pyrimidines
Naliapara, Yogesh,Pandya, Dhananjay
, p. 294 - 302 (2020/04/21)
A series of novel 5H-Thiochromeno[4,3-d]pyrimidine derivatives were synthesized, purified and characterized by different spectroscopy techniques such as1H NMR,13C NMR, Mass and Elemental Analysis. The new compounds were evaluated for their anti-cervical cancer activity on Human Cervical Cell Line HeLa. They were found to be potent anti-cervical cancer agents with GI50 values less than 10 μg/mL with respect to positive control drug Adriamycin.
Design, synthesis, and biological evaluation of 4-chloro-2H-thiochromenes featuring nitrogen-containing side chains as potent antifungal agents
Wang, Dan-Jiao,Hou, Zhuang,Xu, Hang,An, Ran,Su, Xin,Guo, Chun
supporting information, p. 3574 - 3578 (2018/10/15)
A series of 4-chloro-2H-thiochromenes featuring nitrogen-containing side chains were designed, synthesized and tested in vitro for their antifungal activities. The results of preliminary antifungal tests showed that most target compounds exhibited good inhibitory activities against Candida albicans, Cryptococcus neoformans, Candida tropicalis. Notably, compounds 10e and 10y showed most potent activity in vitro against a variety of fungal pathogens with low MICs. Meanwhile, low cytotoxicity on mammalian cells has been observed for compounds 10e and 10y in the tested concentrations by the MTT assay. Therefore, the 4-chloro-2H-thiochromenes with nitrogen-containing groups provide new lead structures in the search for novel antifungal agents.
