195877-39-5 Usage
Chemical structure
Contains a piperidine ring with a BOC protecting group at the 1-position and a CBZ protecting group at the 4-position.
Functional groups
Features an amino group and a methoxycarbonyl-ethyl group, both protected by the BOC group.
Application
Commonly used in organic synthesis as a building block for the construction of more complex molecules.
Industry relevance
Widely used in the pharmaceutical industry due to the prevalence of the piperidine moiety in many drug compounds.
Role
Serves as an important intermediate in the synthesis of various pharmaceuticals and biologically active compounds.
Protecting groups
Utilizes BOC and CBZ groups to protect the amino and methoxycarbonyl-ethyl functionalities during synthesis.
Synthesis
Can be synthesized through various chemical reactions, often involving the formation of the piperidine ring and subsequent protection of functional groups.
Stability
The presence of protecting groups enhances the stability of the molecule during synthetic processes.
Reactivity
The protected functional groups can be selectively deprotected when needed, allowing for further modification and incorporation into more complex structures.
Biological activity
The final products synthesized using this compound may exhibit various biological activities, depending on the specific application and target.
Check Digit Verification of cas no
The CAS Registry Mumber 195877-39-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,8,7 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 195877-39:
(8*1)+(7*9)+(6*5)+(5*8)+(4*7)+(3*7)+(2*3)+(1*9)=205
205 % 10 = 5
So 195877-39-5 is a valid CAS Registry Number.
195877-39-5Relevant articles and documents
Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety
Adang, Anton E. P.,Peters, Co A. M.,Gerritsma, Siene,De Zwart, Edwin,Veeneman, Gerrit
, p. 1227 - 1232 (2007/10/03)
2-Amino-3-piperidin-4-yl-propionic acid containing peptidomimetics are potent protease inhibitors when combined with an appropriate keto-thiazole or keto-carboxylic acid moiety. A novel P1 residue in factor Xa and thrombin inhibitors has been found resulting in IC50 values as low as 0.048 μM, a factor of ten more potent than Argatroban. Starting with non-chiral synthetic routes, a new stereospecific route was developed as well as a new solid- phase method.
