195986-82-4 Usage
General Description
7-METHYL-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE is a chemical compound with a molecular formula of C11H14N2. It is a heterocyclic compound with a seven-membered ring structure and contains a diazepine ring. 7-METHYL-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE, also known as 7-methylbenzo[e][1,4]diazepine, has potential applications in the field of medicinal chemistry and drug development. It may exhibit various pharmacological activities due to its unique chemical structure and may be used as a building block in the synthesis of pharmaceutical compounds. Further research and study are necessary to fully understand the potential uses and properties of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 195986-82-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,5,9,8 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 195986-82:
(8*1)+(7*9)+(6*5)+(5*9)+(4*8)+(3*6)+(2*8)+(1*2)=214
214 % 10 = 4
So 195986-82-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2/c1-8-3-2-4-9-7-11-5-6-12-10(8)9/h2-4,11-12H,5-7H2,1H3
195986-82-4Relevant articles and documents
Discovery and structure-activity relationships of imidazole-containing tetrahydrobenzodiazepine inhibitors of farnesyltransferase
Ding, Charles Z.,Batorsky, Roberta,Bhide, Rajeev,Chao, Hannguang J.,Cho, Young,Chong, Saeho,Gullo-Brown, Johnni,Guo, Peng,Kim, Soong Hoon,Lee, Frank,Leftheris, Katerina,Miller, Arthur,Mitt, Toomas,Patel, Manorama,Penhallow, Becky A.,Ricca, Carol,Rose, William C.,Schmidt, Robert,Slusarchyk, William A.,Vite, Gregory,Yan, Ning,Manne, Veeraswamy,Hunt, John T.
, p. 5241 - 5253 (2007/10/03)
2,3,4,5-Tetrahydro-1-(imidazol-4-ylalkyl)-1,4-benzodiazepines were found to be potent inhibitors of farnesyltransferase (FT). A hydrophobic substituent at the 4-position of the benzodiazepine, linked via a hydrogen bond acceptor, was important to enzyme i