19611-17-7Relevant articles and documents
Reaction of arylethanals with boron tribromide
Dupont, Romain,Cotelle, Philippe
, p. 8457 - 8460 (1998)
Treatment of arylethanals 1 with boron tribromide give 2- phenylnaphthalenes 2 or 1,2,9,10-tetrahydro-1,9- epoxydibenzo[a,e]cyclooctenes 3 by a tandem aldol condensation- intramolecular Friedel-Crafts cyclization or a condensation at the O-position followed by a double Friedel-Crafts alkylation respectively. In all cases, a total demethylation of the methoxy groups occurs.
A tandem annulation with a [1,3]-hydride transfer as the key step leading to isochromans
Wang, Yingwei,Li, Guangxun,Liu, Hongxin,Tang, Zhuo,Cao, Yuan,Zhao, Gang
supporting information, p. 10652 - 10655 (2017/10/06)
An unprecedented method that enables the direct coupling of an α-C-H bond in alcohols with 2-arylacetaldehydes through a [1,3]-hydride transfer ([1,3]-HT) of oxocarbenium ions catalyzed by a Lewis acid has been developed. The redox neutral preparation of
Synthesis of 2-phenylnaphthalenes from styryl-2-methoxybenzenes
Mudududdla, Ramesh,Sharma, Rohit,Abbat, Sheenu,Bharatam, Prasad V.,Vishwakarma, Ram A.,Bharate, Sandip B.
supporting information, p. 12076 - 12079 (2015/02/19)
A new simple and efficient method for the synthesis of 2-phenylnaphthalenes from electron-rich 1-styryl-2-methoxybenzenes has been described. The reaction proceeds via TFA catalyzed C-C bond cleavage followed by intermolecular [4+2]-Diels-Alder cycloaddition of an in situ formed styrenyl trifluoroacetate intermediate. The quantum chemical calculations identified the transition state for the cycloaddition reaction and helped in tracing the reaction mechanism. The method has been efficiently utilized for synthesis of the phenanthrene skeleton and a naphthalene-based potent and selective ER-β agonist. This journal is