19658-59-4 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. Carbonyl chloride derivative
Explanation
The compound contains a carbonyl chloride group (C=O) bonded to a carbon atom.
3. Dioxoloquinoline structure
Explanation
The compound has a fused ring system consisting of a dioxolane ring (a six-membered ring with two oxygen atoms) and a quinoline ring (a tricyclic system with a benzene and a pyridine ring fused together).
4. Ethyl substituent
Explanation
The compound has an ethyl group (-CH2CH3) attached to the dioxoloquinoline structure.
5. 5,8-dihydro
Explanation
The compound has two hydrogen atoms (dihydro) incorporated into the molecule, specifically at positions 5 and 8 of the dioxoloquinoline structure.
6. 8-oxo
Explanation
The compound has an oxygen atom (oxo) at position 8 of the dioxoloquinoline structure, indicating the presence of a carbonyl group (C=O) at that position.
7. Used in organic synthesis
Explanation
The compound serves as a building block or intermediate in the synthesis of various organic compounds.
8. Pharmaceutical research
Explanation
The compound is utilized in the development of biologically active compounds, which may have potential applications in the pharmaceutical industry.
9. Biologically active compounds
Explanation
The compound can be used to create molecules with biological activity, which may have therapeutic or medicinal properties.
10. Valuable and versatile intermediate
Explanation
Due to its unique structure and reactivity, the compound is considered a valuable and versatile intermediate in the development of new drugs and other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 19658-59-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,5 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 19658-59:
(7*1)+(6*9)+(5*6)+(4*5)+(3*8)+(2*5)+(1*9)=154
154 % 10 = 4
So 19658-59-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H10ClNO4/c1-2-15-5-8(13(14)17)12(16)7-3-10-11(4-9(7)15)19-6-18-10/h3-5H,2,6H2,1H3
19658-59-4Relevant articles and documents
Dual role of Rh(III) catalyst enables regioselective halogenation of (electron-rich) heterocycles
Schr?der, Nils,Lied, Fabian,Glorius, Frank
supporting information, p. 1448 - 1451 (2015/02/19)
The Rh(III)-catalyzed selective bromination and iodination of electron-rich heterocycles is reported. Kinetic investigations show that Rh plays a dual role in the bromination, catalyzing the directed halogenation and preventing the inherent halogenation of these substrates. As a result, this method gives highly selective access to valuable halogenated heterocycles with regiochemistry complementary to those obtained using uncatalyzed approaches, which rely on the inherent reactivity of these classes of substrates. Furans, thiophenes, benzothiophenes, pyrazoles, quinolones, and chromones can be applied.
Synthesis of 5-ethyl-8-oxo-5.8-dihydro-1,3-dioxolo [4,5-g] quinolines and related compounds
Pednekar, Suhas,Pandey, Anil Kumar
experimental part, p. 357 - 360 (2011/12/16)
Condensation of N-ethyl-3,4-methylenedioxyaniline 1 with diethyl ethoxymethylenemalonate 2 gave the unsaturated ester 3 which on thermal cyclization in refluxing diphenyl oxide gave ester 4. The ester on basic hydrolysis formed free acid 5 which upon treatment with thionyl chloride gave the acid chloride 6. Treatment of 6 with o-phenylenediamine, hydrazine hydrate, ammonia, urea and thiourea gave the amides (7-11). CS2 treatment in presence of KOH on 8 gave 12. 7-12 were prepared by conventional as well as under microwave irradiation. These compounds have been characterized on the basis of elemental analysis, IR, NMR and MS data.
