197584-93-3Relevant articles and documents
Diversity-oriented synthesis for novel, selective and drug-like inhibitors for a phosphatase from Mycobacterium tuberculosis
He, Rongjun,Bai, Yunpeng,Yu, Zhi-Hong,Wu, Li,Gunawan, Andrea Michelle,Zhang, Zhong-Yin
, p. 1496 - 1499 (2014/12/10)
Mycobacterium protein tyrosine phosphatase B (mPTPB) is a potential drug target of tuberculosis (TB). Using small molecule inhibitors of mPTPB could be a treatment to overcome emerging TB drug resistance. Using a Diversity-Oriented Synthesis (DOS) strateg