197853-31-9 Usage
General Description
L 778,123 is a chemical compound that belongs to the class of nitrofuran antibiotics, which are used to treat bacterial infections. It is known to have broad-spectrum activity against a variety of Gram-positive and Gram-negative bacteria, as well as some protozoa. L 778,123 has been studied for its potential in treating various infections, including urinary tract infections, gastrointestinal infections, and skin infections. L 778,123 works by inhibiting bacterial DNA synthesis, which ultimately leads to the death of the bacteria. While its precise mechanism of action is not fully understood, it is considered to be a promising antibiotic with potential clinical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 197853-31-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,8,5 and 3 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 197853-31:
(8*1)+(7*9)+(6*7)+(5*8)+(4*5)+(3*3)+(2*3)+(1*1)=189
189 % 10 = 9
So 197853-31-9 is a valid CAS Registry Number.
197853-31-9Relevant articles and documents
Oxo-piperazine derivatives of N-arylpiperazinones as inhibitors of farnesyltransferase
Dinsmore, Christopher J,Bergman, Jeffrey M,Wei, Donna D,Zartman,Davide, Joseph P,Greenberg, Ian B,Liu, Dongming,O'Neill, Timothy J,Gibbs, Jackson B,Koblan, Kenneth S,Kohl, Nancy E,Lobell, Robert B,Chen, I-Wu,McLoughlin, Debra A,Olah, Timothy V,Graham, Samuel L,Hartman, George D,Williams, Theresa M
, p. 537 - 540 (2007/10/03)
The evaluation of SAR associated with the insertion of carbonyl groups at various positions of N-arylpiperazinone farnesyltransferase inhibitors is described herein. 1-Aryl-2,3-diketopiperazine derivatives exhibited the best balance of potency and pharmac