19922-07-7 Usage
General Description
5-Amino-3-(4-chlorophenyl)-1,2,4-thiadiazole is a chemical compound with the molecular formula C8H6ClN3S. It comes under the category of organosulfur compounds. Note that the structure of this compound features a thiadiazole ring, thus it is part of the heterocyclic aromatic compounds family. The incorporation of the chlorine-substituted phenyl group and the amino group contributes to its reactivity and potential applications. Despite its specific name, precise details regarding its physiological and ecological properties, potential uses, and safety information are not widely available, suggesting the compound may be primarily of interest for research and development purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 19922-07-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,9,2 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19922-07:
(7*1)+(6*9)+(5*9)+(4*2)+(3*2)+(2*0)+(1*7)=127
127 % 10 = 7
So 19922-07-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClN3S/c9-6-3-1-5(2-4-6)7-11-8(10)13-12-7/h1-4H,(H2,10,11,12)
19922-07-7Relevant articles and documents
One-Pot Synthesis of 3-Aryl-5-amino-1,2,4-thiadiazoles from Imidates and Thioureas by I2-Mediated Oxidative Construction of the N–S Bond
Chai, Ling,Lai, Zhenzhen,Xia, Qiangqiang,Yuan, Jiangpei,Bian, Qilong,Yu, Mingjian,Zhang, Wenkai,Xu, Yuanqing,Xu, Hao
, p. 4338 - 4344 (2018/08/31)
A simple and practical method for the one-pot synthesis of 3-aryl-5-amino-1,2,4-thiadiazoles from imidates and thioureas has been developed. The protocol proceeds through sequential base-mediated nucleophilic addition-elimination reactions and an I2-mediated oxidative coupling for the N–S bond formation. The approach employes readily available and nontoxic substrates and a simple workup to provide 3-aryl-5-amino-1,2,4-thiadiazoles that have a free or substituted amino group.
