19941-83-4Relevant articles and documents
Total syntheses of the diterpenoids (-)-kolavenol and ( -)-agelasine B
Piers, Edward,Roberge, Jacques Y.
, p. 6923 - 6926 (1992)
The trans-clerodane diterpenoids (-)-kolavenol (2) and (-)-agelasine B (1) have been prepared from the enantiomerically pure decalone 3. The key steps of the syntheses involve the stereo selective alkylation of the nitrile 4 (to give 5), the efficient coupling of the iodides 10 and 11 to produce the clerodane skeleton 12, and the electrochemical reduction of 16 to provide (-)-1.
-
Kusumoto,S. et al.
, p. 812 - 820 (1969)
-
TERPENOID COMPOUNDS FROM PARENTUCELLIA LATIFOLIA
Urones, J. G.,Marcos, I. S.,Cubillo, L.,Garrido, N. Martin,Basabe, P.
, p. 2223 - 2228 (2007/10/02)
Together with phytol, sitosterol acetate, α-tocopherylquinone annd sitosterol, the neutral part of Parentucellia latifolia afforded seven esters of diterpene alcohols: 7,13E-labdadien-15-ol acetate; ent-3,13E-clerodadien-15-ol acetat; di-malonate; 7,13E-labdadien-15-yl and ent-3,13E-clerodadien-15-yl malonic acid diester; di- malonate; 7,13E-labdadien-15-yl-methyl malonic acid diester; ent-3-13E-clerodadien-15-yl-methyl malonic acid diester.Three nor diterpenes: 14,15-dinor-7-labden-13-one; 14,15-dinor-ent-3-cleroden-13-one; 14,15-dinor-ent-2,4(18)clerodadien-13-one; and seven diterpene alcohols, five of them isolated as acetyl derivatives: 7,13E-labdadien-15-ol; ent-3,13E-clerodadien-15-ol; diacetate of 8,(17),13E-labdadien-7α,15-diol; 15-acetoxy-13E-labden-8β-ol; 15-acetoxy-13E-labden-8-ol and 15-acetoxy-ent-3,13E-clerodadien-2-one.
