200000-54-0 Usage
Description
N-BENZYL-4-FLUOROPHENYLGLYCINE, also known as N-(4-Fluorophenyl)glycine benzyl ester, is a chemical compound that belongs to the class of glycine derivatives. It is a white to off-white solid with a molecular formula of C15H14FNO2 and a molecular weight of 261.28 g/mol. N-BENZYL-4-FLUOROPHENYLGLYCINE is known for its potential pharmacological properties and is commonly used as an intermediate for the synthesis of pharmaceuticals and agrochemicals. It is important to handle this compound with care and adhere to proper safety measures when working with it in laboratory settings.
Uses
Used in Pharmaceutical Industry:
N-BENZYL-4-FLUOROPHENYLGLYCINE is used as an intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be incorporated into the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
N-BENZYL-4-FLUOROPHENYLGLYCINE is also used as an intermediate in the synthesis of agrochemicals. Its properties make it suitable for the development of new compounds with potential applications in agriculture, such as pesticides or herbicides.
Used in Research and Development:
Due to its potential pharmacological properties, N-BENZYL-4-FLUOROPHENYLGLYCINE is used in research and development for the discovery and optimization of new drug candidates. Its unique structure can be modified and studied to understand its interactions with biological targets and to develop more effective treatments for various diseases.
Used in Laboratory Settings:
N-BENZYL-4-FLUOROPHENYLGLYCINE is used in laboratory settings for the synthesis and testing of new compounds. Researchers can use this intermediate to create and study novel molecules with potential applications in various fields, including medicine, agriculture, and other industries. Proper safety measures should be followed when handling this compound in the laboratory.
Check Digit Verification of cas no
The CAS Registry Mumber 200000-54-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,0,0,0 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 200000-54:
(8*2)+(7*0)+(6*0)+(5*0)+(4*0)+(3*0)+(2*5)+(1*4)=30
30 % 10 = 0
So 200000-54-0 is a valid CAS Registry Number.
200000-54-0Relevant articles and documents
Synthesis of α-amino acids through samarium(II) iodide promoted reductive coupling of nitrones with CO2
Prikhod'Ko, Alexander,Walter, Olaf,Zevaco, Thomas A.,Garcia-Rodriguez, Jaime,Mouhtady, Omar,Py, Sandrine
supporting information; experimental part, p. 3742 - 3746 (2012/09/25)
Several N-benzylnitrones reacted with carbon dioxide in the presence of samarium(II) iodide leading to α-amino acids as the products of reductive C-C coupling. The best selectivities were observed at a carbon dioxide pressure of 50 bar at ambient temperature. The influences of different functional groups in the nitrone backbone and of the coordinating additives to samarium(II) iodide on the product distribution were investigated. The racemic α-amino acids were obtained in up to 70% yield based on HPLC data. A novel approach to the synthesis ofα-amino acids is disclosed, involvingC-carboxylation of nitrones by gaseous CO2 under reductive coupling reaction conditions (SmI2, 0.1 M in THF) at ambient temperature and 50 bar of CO 2 pressure. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Polymorphic form of a tachykinin receptor antagonist
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, (2008/06/13)
This invention is concerned with a novel polymorphic form of the compound 2-(R)-(1-(R)-(3,5-bis(trifluoromethyl)-phenyl)-ethoxy)-3-(S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazolo)methylmorpholine which is a tachykinin receptor antagonist useful in the treatment or prevention of disorders of the central nervous system, inflammatory diseases, pain or migraine, asthma, and emesis. The instant polymorphic form has advantages over the other known forms of 2-(R)-(1-(R)-(3,5-bis(trifluoro-methyl)-phenyl)ethoxy)-3-(S)-(4-fluoro)phenyl-4-(3-(5-oxo-1H,4H-1,2,4-triazolo)methylmorpholine in terms of thermodynamic stability and suitability for inclusion in pharmaceutical formulations.
MORPHOLINE AND THIOMORPHOLINE TACHYKININ RECEPTOR ANTAGONISTS
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, (2008/06/13)
Substituted heterocycles of the general structural formula: STR1 are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis, and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.
