3995-30-0 Usage
Type of compound
PARP inhibitor
Function
Interferes with the repair of DNA damage in cancer cells, leading to their destruction
Potency
Potent inhibitor of PARP enzymes
Mechanism of action
Prevents the repair of damaged DNA in cancer cells, ultimately leading to their death
Approved uses
a. Maintenance therapy for patients with recurrent ovarian cancer who have responded to platinum-based chemotherapy
b. Treatment for patients with germline or somatic BRCA-mutated breast cancer
Investigational uses
a. Other types of cancer
b. Therapy for patients with non-Hodgkin lymphoma
Cancer types targeted
Ovarian and breast cancer
Additional information
Rucaparib is a chemical compound used in the treatment of ovarian and breast cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 3995-30-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,9 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3995-30:
(6*3)+(5*9)+(4*9)+(3*5)+(2*3)+(1*0)=120
120 % 10 = 0
So 3995-30-0 is a valid CAS Registry Number.
