49759-34-4Relevant articles and documents
A Convenient Method for the Synthesis of Macrocyclic Tetra-amides by Double Condensation Reaction
Okuno, Yohmei,Horita, Kiyoshi,Yonemitsu, Osamu,Shibata, Kazue,Amemiya, Toshiyuki,Holm, Richard H.
, p. 1115 - 1118 (2007/10/02)
A facile condensation reaction between bifunctional amines and carboxylic acid derivatives has been found to be very efficient for the formation of macrocyclic tetra-amide ring, and tetralactams with 33- to 37-membered rings were readily synthesized in good yield (60-90percent).