69914-27-8 Usage
General Description
[2,2-bis(methylsulfonyl)ethenyl]benzene is a chemical compound with the molecular formula C10H12O4S2. It is also known by its trade name DMEB, and is frequently used in the synthesis of various organic materials such as polymeric materials and pharmaceuticals. It is also a key intermediate in the production of a variety of substances including dyes, pigments, agrochemicals, and specialty chemicals. Furthermore, [2,2-bis(methylsulfonyl)ethenyl]benzene is known for its ability to act as a strong nucleophile in reactions, and has been studied as a potential reagent in various chemical transformations. Additionally, it is important to handle this compound with caution as it is considered to be a potentially hazardous substance and may pose risks to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 69914-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,9,1 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 69914-27:
(7*6)+(6*9)+(5*9)+(4*1)+(3*4)+(2*2)+(1*7)=168
168 % 10 = 8
So 69914-27-8 is a valid CAS Registry Number.
69914-27-8Relevant articles and documents
Base-free Enantioselective C(1)-Ammonium Enolate Catalysis Exploiting Aryloxides: A Synthetic and Mechanistic Study
McLaughlin, Calum,Slawin, Alexandra M. Z.,Smith, Andrew D.
supporting information, p. 15111 - 15119 (2019/11/05)
An isothiourea-catalyzed enantioselective Michael addition of aryl ester pronucleophiles to vinyl bis-sulfones via C(1)-ammonium enolate intermediates has been developed. This operationally simple method allows the base-free functionalization of aryl esters to form α-functionalized products containing two contiguous tertiary stereogenic centres in excellent yield and stereoselectivity (all ≥99:1 er). Key to the success of this methodology is the multifunctional role of the aryloxide, which operates as a leaving group, Br?nsted base, Br?nsted acid and Lewis base within the catalytic cycle. Comprehensive mechanistic studies, including variable time normalization analysis (VTNA) and isotopologue competition experiments, have been carried out. These studies have identified (i) orders of all reactants; (ii) a turnover-limiting Michael addition step, (iii) product inhibition, (iv) the catalyst resting state and (v) catalyst deactivation through protonation.
