79952-57-1Relevant articles and documents
Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents
Procopio, Antonio,Alcaro, Stefano,Cundari, Sante,De Nino, Antonio,Ortuso, Francesco,Sacchetta, Paolo,Pennelli, Alfonso,Sindona, Giovanni
, p. 6084 - 6089 (2007/10/03)
Changes in the GSH/GST system have been found to correlate with resistance to anticancer alkylating agents, presumably through accelerated detoxification of these drugs since some GSTs have been shown to catalyze the conjugation of GSH to specific antineo