1001438-56-7Relevant articles and documents
Liquid forms of pharmaceutical co-crystals: Exploring the boundaries of salt formation
Bica, Katharina,Shamshina, Julia,Hough, Whitney L.,MacFarlane, Douglas R.,Rogers, Robin D.
supporting information; experimental part, p. 2267 - 2269 (2011/04/22)
We present evidence of hydrogen bond formation, not salt formation, as the driving force in the liquefaction of a solid pharmaceutical in the form of a neutral acid-base complex, as exemplified by the liquid formed from a mixture of the local anesthetic l