100189-17-1

Basic information

• Product Name: 6-Methyl-3-pyridineethanol
• Synonyms: 3-Pyridineethanol,6-methyl-(9CI);3-PYRIDINEETHANOL, 6-METHYL;6-methyl-3-Pyridineethanol;6-Methylpyridine-3-ethanol ;2-(6-methylpyridin-3-yl)ethanol;2-(6-Methyl-[3]pyridyl)-ethanol;2-(6-Methylpyridin-3-yl)ethan-1-ol
• CAS NO: 100189-17-1
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.18
• Product Categories: PYRIDINE
• Mol File: 100189-17-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 38 °C
• Boiling Point: 246.739 °C at 760 mmHg
• Flash Point: 103.025 °C
• Appearance: /
• Density: 1.061 g/cm³
• Vapor Pressure: 0.014mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.61±0.10(Predicted)
• CAS DataBase Reference: 6-Methyl-3-pyridineethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methyl-3-pyridineethanol(100189-17-1)
• EPA Substance Registry System: 6-Methyl-3-pyridineethanol(100189-17-1)

Safety Data

• Hazardous Substances Data: 100189-17-1(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

6-Methyl-3-pyridineethanol is a reactant used in organic synthesis.

InChI:InChI=1/C8H11NO/c1-7-2-3-8(4-5-10)6-9-7/h2-3,6,10H,4-5H2,1H3

Upstream product

• 19733-96-1 2-(6-methylpyridin-3-yl)acetic acid 
• 3430-13-5 5-bromo-2-methylpyridine 
• 140-76-1 2-methyl-5-vinylpyridine 
• 36357-38-7 1-(6-methyl-pyridin-3-yl)-ethanone 

Downstream Products

• 1147893-28-4 5-(2-bromoethyl)-2-methylpyridine 
• 3613-73-8 dimebon 

Relevant articles and documents

Hydroboration. 75. Directive Effects in the Hydroboration of Vinyl and Propenyl Heterocycles with Representative Hydroborating Agents

The hydroboration of representative heterocyclic compounds bearing a vinyl or propenyl substituent with borane-methyl sulfide (BMS), 9-borabicyclononane (9-BBN), dicyclohexylborane (Chx2BH), and disiamylborane (Sia2BH) was investigated systematically to establish directive effects in the hydroboration.The directive effects observed for 2-vinylfuran and 2-vinylthiophene are similar to those realized in styrene.The hydroboration of vinylpyridine required an excess of borane hydroborating agent.Alternatively, the nitrogen atom could be protected by complexing with boron trifluoride.When the vinyl group is ortho or para to the pyridine nitrogen, α-organoboranes are the major products in the hydroboration.However, when the vinyl group is meta to the pyridine nitrogen, β-organoboranes are formed predominantly.Hydroboration of the vinyl-pyridine-BF3 complexes results in an increase in the formation of α-organoboranes, as compared to β.The distribution of boron in the hydroboration of 2-propenyl heterocyclic compounds compared to that of trans-1-propenylbenzene showed that the effect of the heterocycle is pronounced in directing the boron atom strongly to the α-carbon atom.

TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; Synthesis of dimebolin

A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl azides. Other catalysts and conditions were neither as selective nor as high-yielding. This method was used to synthesize dimebolin in a concise and efficient manner.