1005001-62-6Relevant articles and documents
Rapid and efficient synthesis of dysiherbaine and analogues to explore structure-activity relationships
Sasaki, Makoto,Tsubone, Koichi,Aoki, Kunimori,Akiyama, Nobuyuki,Shoji, Muneo,Oikawa, Masato,Sakai, Ryuichi,Shimamoto, Keiko
, p. 264 - 273 (2008/09/17)
(Chemical Equation Presented) A rapid and efficient total synthesis of dysiherbaine (1), a potent and subtype-selective agonist for ionotropic glutamate receptors, has been accomplished. A key intermediate 15 was synthesized by two approaches. The first s