10057-46-2 Usage
General Description
5-Trifluoromethyl-1H-benzoimidazol-2-ylamine is a chemical compound with the molecular formula C8H6F3N3. It is a heterocyclic compound containing a benzene ring fused to an imidazole ring, with a trifluoromethyl group attached to the benzene ring. 5-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-2-YLAMINE is used in the synthesis of various pharmaceuticals and agrochemicals, as well as in the research and development of new chemical products. It exhibits a range of biological activities and has potential application as a building block in the development of new therapeutic agents. Additionally, it is used as a reagent in organic chemistry for the modification of other molecules to introduce the 5-trifluoromethyl-1H-benzoimidazol-2-ylamine moiety.
Check Digit Verification of cas no
The CAS Registry Mumber 10057-46-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,5 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10057-46:
(7*1)+(6*0)+(5*0)+(4*5)+(3*7)+(2*4)+(1*6)=62
62 % 10 = 2
So 10057-46-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F3N3/c9-8(10,11)4-1-2-5-6(3-4)14-7(12)13-5/h1-3H,(H3,12,13,14)
10057-46-2Relevant articles and documents
BENZIMIDAZOLE DERIVATIVES AS RAF KINASE INHIBITORS
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Page/Page column 122-123, (2010/02/10)
The present invention relates to benzimidazole derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula I or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase pathways, preferably by the raf kinase pathway, especially cancers, [FORMULA]
