100783-51-5

Basic information

• Product Name: 2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxy-
• Synonyms: 2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxy-
• CAS NO: 100783-51-5
• Molecular Formula: C15H19NO5
• Molecular Weight: 293.32
• Mol File: 100783-51-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxy-(100783-51-5)
• EPA Substance Registry System: 2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxy-(100783-51-5)

Safety Data

• Hazardous Substances Data: 100783-51-5(Hazardous Substances Data)

Usage

Description

2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxyis a complex organic compound characterized by a fused oxazine and isoquinoline ring system. It is a tetrahydro derivative with substituents at positions 1, 6, 7, and 11b, including a hydroxymethyl group and two methoxy groups. This unique structure endows it with potential pharmacological activity, making it a compound of interest for further study in medicinal chemistry and drug development.

Uses

Used in Pharmaceutical Industry:
2H,4H-[1,3]Oxazino[4,3-a]isoquinolin-4-one, 1,6,7,11b-tetrahydro-1-(hydroxymethyl)-9,10-dimethoxyis used as a potential pharmaceutical agent for its possible pharmacological activity. The specific application reason is due to its unique structure, which may contribute to its efficacy in treating certain conditions or diseases. Further research and development are necessary to explore its full potential in this industry.

Upstream product

• 98661-42-8 1--6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 541-41-3 chloroformic acid ethyl ester 
• 99082-51-6 1--2-ethoxycarbonyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

STEREOCHEMICAL STUDIES, 145. SATURATED HETEROCYCLES, 152. PREPARATION AND CONFORMATIONAL ANALYSIS OF STEREOISOMERIC 1,6,7,11b-TETRAHYDRO-2HOXAZINOISOQUINOLIN-4-ONE DERIVATIVES

Starting from 1--6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 3a, trifunctional 1,2,3,4-tetrahydroisoquinolines were synthetized.From the N-ethoxycarbonyl derivative of 3a, (r-11b,c-1)-1-hydroxymethyl- (8) and (r-11b,t-1)-1-chloromethyl-9,10-dimethoxy-1,6,7,11b-tetrahydro-2Hoxazinoisoquinolin-4-one (9) were formed in unexpected reactions.High-resolution NMR revealed that the tetrahydroisoquinoline-fused C-1 epimer oxazinone derivatives 8 and 9 have different conformations in solution.The first X-ray diffraction evidence of the presence of two different conformations of oxazinoisoquinolines 8 and 9 in the solid state is provided.