101095-67-4Relevant articles and documents
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
Gezegen, Hayreddin,Gürdere, Meliha B.,Din?er, Ay?egül,?zbek, O?uz,Ko?yi?it, ümit M.,Taslimi, Parham,Tüzün, Burak,Budak, Yakup,Ceylan, Mustafa
, (2020/12/13)
A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase (α-Gly). The new cya
Synthesis and Biological Evaluation of Novel 1-(4-(Hydroxy(1-oxo-1,3-dihydro-2H-inden-2-ylidene)methyl)phenyl)-3-phenylurea Derivatives
Gezegen, Hayreddin,Hepokur, Ceylan,Tutar, U?ur,Ceylan, Mustafa
, (2017/10/24)
A series of novel phenylurea containing 2-benzoylindan-1-one derivatives 3a?–?3j were synthesized from the reaction of phenylurea-substituted acetophenones 1a?–?1j with phthalaldehyde 2 under mild reaction conditions in good yields. All synthesized compou
DIARYL UREAS AS CB1 ANTAGONISTS
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Page/Page column 57, (2008/06/13)
Compounds of Formula I are provided. In which the variables are as described herein. Such compounds may be used to modulate CB1 activity in vivo or in vitro, and are particularly useful in the treatment of conditions responsive to CB1 modulation in humans, domesticated companion animals and livestock animals, including appetite disorders, obesity and addictive disorders. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies and various in vitro assays.