101646-18-8Relevant articles and documents
2-CARBETHOXY-4H-3,1-BENZOXAZIN-4-ONE. 1. SYNTHESIS AND REACTION MECHANISM OF FORMATION
Ukrainets, I. V.,Bezuglyi, P. A.,Treskach, V. I.,Slobodzyan, S. V.
, p. 903 - 907 (1991)
The possibility was examined of using various condensing agents in the intramolecular cyclization reaction of ethyl ester of 2-carbomalonanilic acid into 2-carboethoxymethyl-4H-3,1-benzoxazin-4-one.It was found that the optimal reagent is dicyclohexylcarbodiimide.By using NMR spectroscopy and deutero-exchange it was shown that the cyclization proceeds with the participation of the hydroxyl group of the carboxyl and a proton of the amide function.
Ethyl Esters of Malonanilic Acids. Synthesis and Pyrolysis
Ukrainets, Igor V.,Bezugly, Peter A.,Treskach, Vladimir I.,Taran, Svetlana G.,Gorokhova, Olga V.
, p. 10331 - 10338 (2007/10/02)
The pyrolysis under 170-220 deg C or boiling in DMF of malonanilic acids ethyl esters (2) is accompanied by formation of malonic acids symmetric dianilides (7) with high yields.A possible mechanism for this transformation has been suggested.
2-CARBETHOXY-4H-3,1- BENZOXAZIN-4-ONE. 2. HYDRAZINOLYSIS
Ukrainets, I. V.,Bezuglyi, P. A.,Treskaya, V. I.,Turov, A. V.,Slobodzyan, S. V.,Gorokhova, O. V.
, p. 907 - 909 (2007/10/02)
3-Amino-2-carboxymethylquinazolin-4(3H)-one was obtained by hydrazinolysis of 2-carbethoxymethyl-4H-3,1-benzoxazin-4-one.Its transformations into 2-hydroxypyrazoloquinazolin-9(1H)-one and 3-amino-2-hydrazido-(or benzylamido)carbonylmethylquinazolin
