1017800-06-4

Basic information

• Product Name: N-[(2R)-2-Hydroxy-2-methoxycarbonylethyl]-N-[4-(4-trifluoromethyl-phenoxy)phenyl]methanesulfonamide
• Synonyms: N-[(2R)-2-Hydroxy-2-methoxycarbonylethyl]-N-[4-(4-trifluoromethyl-phenoxy)phenyl]methanesulfonamide
• CAS NO: 1017800-06-4
• Molecular Weight: 433.405
• Mol File: 1017800-06-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-[(2R)-2-Hydroxy-2-methoxycarbonylethyl]-N-[4-(4-trifluoromethyl-phenoxy)phenyl]methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(2R)-2-Hydroxy-2-methoxycarbonylethyl]-N-[4-(4-trifluoromethyl-phenoxy)phenyl]methanesulfonamide(1017800-06-4)
• EPA Substance Registry System: N-[(2R)-2-Hydroxy-2-methoxycarbonylethyl]-N-[4-(4-trifluoromethyl-phenoxy)phenyl]methanesulfonamide(1017800-06-4)

Safety Data

• Hazardous Substances Data: 1017800-06-4(Hazardous Substances Data)

Upstream product

• 1008530-98-0 N-[4-(4-trifluoromethylphenoxy)phenyl]methanesulfonamide 
• 4538-50-5 methyl (2R)-glycidate 

Downstream Products

• 1017800-11-1 N-[(2R)-2-methoxycarbonyl-2-trifluoromethanesulfonyloxyethyl]-N-[4-(4-trifluoromethylphenoxy)phenyl]methanesulfonamide 

Relevant articles and documents

HETEROCYCLIC DERIVED METALLOPROTEASE INHIBITORS

This invention provides novel heterocyclic derived matrix metalloprotease inhibitors of the formula: and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by antagonizing matrix metalloproteases. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions.

β-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: Part 2. Optimization of α-amino substituents

The introduction and the optimization of an α-amino substituent based on a series of α-hydroxy-β-N-biaryl ether sulfonamide hydroxamates is described. The modification leads to a new series of MMP-2/MMP-9 inhibitors with enhanced inhibitory activities and