101893-55-4

Basic information

• Product Name: 2-methyl-3-benzylpyridine
• Synonyms: 2-methyl-3-benzylpyridine
• CAS NO: 101893-55-4
• Molecular Weight: 183.253
• Mol File: 101893-55-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methyl-3-benzylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-3-benzylpyridine(101893-55-4)
• EPA Substance Registry System: 2-methyl-3-benzylpyridine(101893-55-4)

Safety Data

• Hazardous Substances Data: 101893-55-4(Hazardous Substances Data)

Upstream product

• 109591-92-6 3-benzyl-2-methyl-piperidine 
• 100-52-7 benzaldehyde 
• 110823-83-1 2-methyl-1,4-bis(trimethylsilyl)-1,4-dihydropyridine 
• 109-06-8 α-picoline 
• 2550-26-7 4-Phenyl-2-butanone 
• 109-76-2 Trimethylenediamine 
• 100-44-7 benzyl chloride 
• 38749-79-0 3-bromo-2-picoline 
• 100-39-0 benzyl bromide 
• 100371-69-5 5-benzylidene-6-methyl-2,3,4,5-tetrahydro-pyridine 

Downstream Products

• 64362-32-9 3-benzoylpyridine-2-carboxylic acid 

Relevant articles and documents

Palladium acetate-catalyzed one-pot synthesis of mono- And disubstitued pyridines

A Pd-catalyzed one-pot synthesis of mono- and disubstituted pyridines was developed. The substituted pyridines were obtained from ketones or an aldehyde and 1,3-diaminopropane using a combination of catalytic Pd(OAc)2 and Cu(OAc)2. High-concentration reaction conditions enabled this catalytic reaction to be acid-free.

Reactions of 1,4-Bis(trimethylsilyl)-1,4-dihydropyridines with Carbonyl Compounds: A New Method for Regioselective Synthesis of 3-Alkylpyridines

A new method for the alkyl group introduction at the 3-position of pyridines is described: Reductive disilylation of pyridine, its 2-methyl, 3-methyl, and 4-methyl derivatives affords the corresponding 1,4-disilyl-1,4-dihydropyridines.Tn the presence of a catalytic amount of tetrabutylammonium fluoride, these dihydropyridines smoothly react with a variety of aldehydes and ketones to give 3-alkylpyridines.