101970-32-5

Basic information

• Product Name: methyl 2-hydroxy-2-(4-isobutylphenyl)propionate
• Synonyms: methyl 2-hydroxy-2-(4-isobutylphenyl)propionate
• CAS NO: 101970-32-5
• Molecular Weight: 236.311
• Mol File: 101970-32-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-hydroxy-2-(4-isobutylphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-hydroxy-2-(4-isobutylphenyl)propionate(101970-32-5)
• EPA Substance Registry System: methyl 2-hydroxy-2-(4-isobutylphenyl)propionate(101970-32-5)

Safety Data

• Hazardous Substances Data: 101970-32-5(Hazardous Substances Data)

Upstream product

• 15687-27-1 ibuprofen 
• 61566-34-5 (+/-)-ibuprofen methyl ester 

Downstream Products

• 180293-49-6 2-fluoro-2-[4-(2-methylpropyl)phenyl]propionic acid 
• 180293-53-2 methyl 2-fluoro-2-[4-(2-methylpropyl)phenyl]propionate 
• 60057-62-7 2-(4-isobutyl-phenyl)-2-hydroxy-propionic acid 

Relevant articles and documents

Highly efficient C-H hydroxylation of carbonyl compounds with oxygen under mild conditions

A transition-metal-free Cs2CO3-catalyzed α-hydroxylation of carbonyl compounds with O2 as the oxygen source is described. This reaction provides an efficient approach to tertiary α-hydroxycarbonyl compounds, which are highly valued chemicals and widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very environmentally friendly and practical. This transformation is highly efficient and highly selective for tertiary C(sp3)-H bond cleavage. OH, so simple! A transition-metal-free Cs2CO 3-catalyzed α-hydroxylation of carbonyl compounds with O 2 provided a variety of tertiary α-hydroxycarbonyl compounds (see scheme; DMSO=dimethyl sulfoxide), which are widely used in the chemical and pharmaceutical industry. The simple conditions and the use of molecular oxygen as both the oxidant and the oxygen source make this protocol very efficient and practical.